ISSN:
1432-0983
Keywords:
Keywords A. nidulans
;
Salt sensitivity
;
Arginase
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Strains of Aspergillus nidulans carrying the sltA1 mutation, conferring sensitivity to KCl and NaCl, also showed an arginine-sensitive phenotype whereby concentrations of the L-amino acid at or above 10 mM were toxic to growth. Sexual progeny of a cross between a sltA1 mutant and a wild-type strain showed a co-segregation of salt and arginine sensitivity. Similarly, revertants to salt tolerance showed a loss of arginine sensitivity as did sltA1 strains that were transformed with a cosmid carrying the putative sltA1 + wild-type allele. In addition, arginine sensitivity could be relieved by L-ornithine. It is suggested that sltA1 is a salt-sensitive allele of the arginase gene (agaA).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002940050072
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