ISSN:
1432-0533
Keywords:
Peripheral neuropathy
;
Diabetes mellitus
;
Arteritis
;
Hypoxic axonopathy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The peripheral nerve was taken from 25 diabetic patients with arteritis just before or after amputation of a leg. The ultrastructural study of myelinated fibers showed several alterations. Loss of fibers varied greatly from case to case. This was accompanied in some cases by hypertrophy of the Schwann cells around demyelinated fibers as has been observed in some ordinary diabetic neuropathies. Unusual abnormalities consisted of particular axonal degeneration and evidence of aberrant remyelination. This axonal injury was peculiar because of the accumulation of organelles which tended to transform some of the fibers into enlarged axons. Such a lesion might correspond to a hypoxic axonopathy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00691990
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