ISSN:
1434-193X
Keywords:
Natural products
;
Antibiotics
;
Macrolides
;
Asymmetric synthesis
;
Chiral sulfoxide
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
This paper describes an efficient stereocontrolled and convergent approach towards the C1-C13 polyol fragment of amphotericin B. The strategy is based on the stereoselective reduction of a chiral β,γ-dioxo-ε-sulfinyl ester to obtain anti- or syn-1,3-diols.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
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