ISSN:
1432-0878
Schlagwort(e):
Alteration of lymphocytes
;
Mast cells
;
Weakening of immune system
;
Aging
;
Atrophy
;
Lymph node
;
Athymic animal
;
Rat (Sprague-Dawley)
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary This paper reports the occurrence of an accumulation of lethally altered lymphocytes in the subcapsular sinus of a compartment or compartments of some lymph nodes, an unusual feature best developed in nodes of the mesenteric site in aging athymic animals. Many of these cells are rod-like. In other compartments, similar lymphocytes occurred at various depths in the nodal parenchyma. This was accompanied by the disappearance of a compartment's populations of normal lymphoid cells. The observations reveal that lymphocytes, altered in a tissue, may reach the subcapsular sinus of the draining node compartment and migrate into its parenchyma which then undergoes atrophy. The likely involvement of mast cells is discussed.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00309881
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