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  • 1990-1994  (3)
  • Miscellaneous Medical  (2)
  • Atypical hyperplasia  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Diagnostic criteria and cancer risk of proliferative breast lesions (1993)
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 53 (1993), S. 59-64 
    Details
    ISSN: 0730-2312
    Schlagwort(e): Atypical hyperplasia ; breast cancer ; cancer risk ; hyperplasia ; family history ; premalignancy ; proliferative disease ; Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Breast cancer risk assessment in women following a benign breast biopsy is a promising area with regard to intermediate endpoint determination, and has been particularly fostered by the consensus agreement concerning the risk attributed to specific diagnoses [1]. Several recent studies have largely verified this approach [2-4], and a recent report demonstrates general agreement among most expert pathologists regarding diagnostic criteria for these lesions [5]. However, in a limited number of cases, determining exact levels of risk for individual patients has been problematic as a result of a failure by pathologists to achieve consensus on diagnostic criteria for these same lesions. This situation has arisen primarily because it is much more tenable to disagree over subjective diagnostic criteria, than it is to argue with robustly supported epidemiological data. Without agreement on reproducible diagnostic criteria, widely promulgated consensus risk estimates for these specific histologic entities are no longer applicable. In addition, those individuals who choose different diagnostic criteria for proliferative breast lesions fail to realize that the terminology, epidemiological risk estimates, and diagnostic criteria used by Dupont and Page are inexorably linked. Since the publication of the consensus statement [1], those using the terms “atypical ductal hyperplasia” and “atypical lobular hyperplasia” have by default accepted the diagnostic criteria of Dupont and Page. Therefore, surgical pathologists who desire to make use of the consensus risk estimates must familiarize themselves with diagnostic criteria for the various histologic entities that comprise proliferative disease of the breast as defined by Dupont and Page [6]. This presentation will concentrate on the importance of a combined histologic and cytologic approach to diagnose proliferative breast lesions, and will specifically focus on usual hyperplasia, atypical ductal hyperplasia, atypical lobular hyperplasia, and both ductal and lobular carcinoma in situ.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jcb.240531111
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  • 2
    Digitale Medien
    Digitale Medien
    Real anatomy lesson: Differential diagnosis in the first year anatomy course (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Clinical Anatomy 4 (1991), S. 51-55 
    Details
    ISSN: 0897-3806
    Schlagwort(e): bicameral data base ; structural non-specifics ; Life and Medical Sciences ; Miscellaneous Medical
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: In designing the medical school curriculum something has to be taught first even though the basic sciences and clinical topics interlock. Students traditionally learn anatomy first and suspend ther bewilderment regarding the eventual application of the structural detail studied. Infinite memory chores are learned with little overall view of how the student's data bank will function in the acute clinical situation. A fundamental charge of physicians is to consider all diagnostic possibilities before implementing treatment. Yet with the current system, first year students find themselves in possession of large volumes of information but are still unable to establish even a rudimentary differential diagnosis. It is suggested that during the first year clinical anatomy course the student be introduced to broad categories of disease using anatomy as the structural foundation for visualizing diagnostic possibilities. Wasteful interludes in the laboratory could be replaced with memory-enhancing dissection using visual, verbal, auditory, and kinesthetic methods coupled with clinically oriented vocabulary expansion. A basic etiologic mnemonic is discussed as a framework for rapid diagnosis. In conjunction with the idea of decreasing medical information overload, we suggest that data presented to medical students in general be organized in a bicameral fashion as either emergent or elective. Anatomists and clinicians should consider rewriting the anatomy manual to include “clinical pathology.”
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ca.980040107
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  • 3
    Digitale Medien
    Digitale Medien
    Anatomical characteristics of the iliopubic tract: Implications for repair of inguinal hernias (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Clinical Anatomy 5 (1992), S. 255-263 
    Details
    ISSN: 0897-3806
    Schlagwort(e): groin ; fascia ; transversus ; Life and Medical Sciences ; Miscellaneous Medical
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The high recurrence rate of inguinal hernias following primary repair has prompted us to re-examine the anatomy of the inguinal region with particular emphasis on the iliopubic tract (IPT). The IPT is described as an aponeurotic band forming the inferior margin of the transversus abdominis lamina. We documented the presence and degree of development of the IPT in dissections of 151 embalmed inguinal regions and in serial sagittal sections of four body halves. The iliopubic tract was identified in all specimens. It stretched between the anterior superior iliac spine laterally and the pubic tubercle and the pubic tubercle and pectineal line medially. The intervening arch formed a discrete structure of variable thickness and was substantial in 63 specimens. Histological sections demonstrated that the IPT is connected to the inguinal ligament, fascia lata, and anterior femoral sheath and is composed primarily of collagenous fibers with a minor elastic component. These data indicate that the iliopubic tract is a consistent and easily identified structure in the inguinal regions. These results suggest that dissection of the iliopubic tract, like the inguinal ligament, should become an integral part of the assessment of groin anatomy during hernia repair. © 1992 Wiley-Liss, Inc.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/ca.980050402
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