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  • 1
    ISSN: 1432-1963
    Keywords: Schlüsselwörter Endophthalmitis ; atypische Mykobakterien ; PCR ; Key words Endophthalmitis ; Atypical mycobacteria ; PCR
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report a case of a 60 year old male who presented with a therapy resistant endophthalmitis which led to an evisceratio bulbi. Histologically, a granulomatous inflammation was present, in which acid-fast bacilli could not be detected. Molecular genetic examination by means of polymerase-chain-reaction technique (PCR) of the routinely processed tissue material revealed the diagnosis of an atypical mycobacterial infection, because DNA specific for atypical mycobacteria was detected. This example shows that PCR technique provides a useful tool in the diagnosis of mycobaterial infections as an adjunct to surgical pathology.
    Notes: Zusammenfassung Es wird über einen 60 Jahre alten Mann berichtet, bei dem wegen einer therapieresistenten Endophthalmitis eine Evisceratio bulbi durchgeführt wurde. Eine histologische Untersuchung erbrachte eine granulomatöse Endophthalmitis, der Nachweis säurefester Stäbchen mit Hilfe der Ziehl-Neelson-Färbung war erfolglos. Mit der Polymerase-Chain-Reaction (PCR) ließen sich jedoch molekulargenetisch atypische Mykobakterien als Ursache der Endophthalmitis nachweisen.
    Type of Medium: Electronic Resource
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