ISSN:
1432-1335
Keywords:
Thyroid tumors
;
Cytology
;
Automatic classification
;
Computer-based cytophotometry
;
Light microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary This study of 14 follicular adenomas, 10 papillary carcinomas and 11 follicular carcinomas of the human thyroid gland demonstrates the possibility of a cytological tumor classification using digital picture processing. Routinely prepared, HE-stained imprints of surgical specimens were scanned under a light microscope at high resolution with a colour TV camera. The cell nuclei were segmented and analysed with an image processing system. The computer-aided cytophotometric methods detected the most significant differences in the chromatin texture with a criteria variance of texture line distances and texture points per texture knots. Using these criteria benign and malignant tumor types could be successfully differentiated.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00390365
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