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  • 1
    Electronic Resource
    Electronic Resource
    Involvement of glibenclamide-sensitive potassium channels in vasorelaxation by cochlear nerve stimulation (1997)
    Springer
    European archives of oto-rhino-laryngology and head & neck 254 (1997), S. S6 
    Details
    ISSN: 1434-4726
    Keywords: Cochlea ; Field stimulation ; Vascular endothelium ; Vasorelaxation ; Glibenclamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Rabbit aortic rings relaxed with an increase in cyclic guanosine monophosphate and cyclic adenosine monophosphate content in response to exposure to organ fluid of isolated cochleas of the guinea pig following field stimulation (50 Hz, 80 V, 0.2 ms). Relaxations were blocked by 30 μMN G-nitro-l-arginine methyl ester added to the vessel rings. This inhibitory effect was reversed by 3 MMl-arginine. Removal of the vascular endothelium also blocked the relaxation response. Glibenclamide attenuated vasorelaxation in a concentration-dependent manner. We conclude that cochlear nerve stimulation induces an endothelium-dependent vasorelaxation involving activation of adenosine triphosphate-sensitive potassium channels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02439710
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Autoradiographic studies on the protein synthesis and the distribution of the newly synthesized proteins in oligodendroglial cells (1975)
    Springer
    Cell & tissue research 159 (1975), S. 267-277 
    Details
    ISSN: 1432-0878
    Keywords: Hippocampus ; Oligodendroglial cells ; Protein synthesis ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The protein-synthesizing activity of oligodendroglial cells in the rat hippocampus as well as the migration of the newly synthesized proteins within these cells were examined by means of light and electron microscopic autoradiography when injecting 3H-leucine into the lateral ventricle. The autoradiographs of oligodendroglial cells were compared with the autoradiographs of hippocampal pyramidal cells of the same area. According to the quantitative evaluation of the autoradiographs the protein-synthesizing activity of the oligodendrocytes equals or may even exceed that of the pyramidal cells. In oligodendroglial cells most of the newly synthesized proteins migrate very rapidly from the rough-surfaced endoplasmic reticulum into the cisternae of the Golgi apparatus and disappear continuously. The proteins disappear from the Golgi apparatus simultaneously with the decrease in the radioactive concentration of the perikaryon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219161
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    Paper (German National Licenses)
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