ISSN:
1432-0878
Keywords:
Hippocampus
;
Oligodendroglial cells
;
Protein synthesis
;
Autoradiography
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The protein-synthesizing activity of oligodendroglial cells in the rat hippocampus as well as the migration of the newly synthesized proteins within these cells were examined by means of light and electron microscopic autoradiography when injecting 3H-leucine into the lateral ventricle. The autoradiographs of oligodendroglial cells were compared with the autoradiographs of hippocampal pyramidal cells of the same area. According to the quantitative evaluation of the autoradiographs the protein-synthesizing activity of the oligodendrocytes equals or may even exceed that of the pyramidal cells. In oligodendroglial cells most of the newly synthesized proteins migrate very rapidly from the rough-surfaced endoplasmic reticulum into the cisternae of the Golgi apparatus and disappear continuously. The proteins disappear from the Golgi apparatus simultaneously with the decrease in the radioactive concentration of the perikaryon.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00219161
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