ISSN:
1432-072X
Keywords:
Zymomonas mobilis
;
Tryptophan biosynthesis
;
Auxotrophs
;
Regulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Tryptophan auxotrophs were isolated and used to analyze the regulation of tryptophan biosynthesis in Zymomonas mobilis. Twelve tryptophan auxotrophs were cassified as trp E, B or A based on accumulation of, or growth on, indole and anthranilic acid. Trp B mutants were found to accumulate indole when grown on limiting, but not on excess tryptophan, suggesting that tryptophan plays a role in regulating its biosynthesis. Tryptophan synthase and indoleglycerol phosphate synthase specific activities were measured in the wild-type strain and two trp mutants grown in limiting or excess tryptophan. Neither activity was repressed by exogenous tryptophan.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00446761
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