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  • 1
    Electronic Resource
    Electronic Resource
    Chlorpromazine and avoidance: A genetic analysis (1974)
    Springer
    Psychopharmacology 34 (1974), S. 309-316 
    Details
    ISSN: 1432-2072
    Keywords: Chlorpromazine ; Recombinant Inbred Strains ; Avoidance Behavior ; Pharmacogenetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chlorpromazine exerts a significantly higher impairment on the performance of C57BL/6By than on BALB/cBy inbred mice pretrained in an active avoidance task. The effects of the drug on this measure assessed in these two strains, their reciprocal F1 hybrids, their recombinant inbred strains, and two C57BL/6By congenic lines indicate that at least two genes modulate the action of chlorpromazine on avoidance behavior. It was possible to characterize one of the loci modulating the effect of chlorpromazine on avoidance performance. We assign the symbol Cpz. The locus is in chromosome 9, Linkage Group II.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422554
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Genetic correlation between open-field activity and defecation: Analysis with the CXB recombinant-inbred strains (1979)
    Springer
    Behavior genetics 9 (1979), S. 349-357 
    Details
    ISSN: 1573-3297
    Keywords: open-field behavior ; genetic, correlation ; CXB recombinant-inbred strains ; illumination conditions ; C57BL/6By mice ; BALB/cBy mice ; BALB/cJ mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Confirming previous investigations involving descendants of C57BL/6J and BALB/cJ mouse strains, significant phenotypic, environmental, and genetic correlations (r=−0.53, −0.24, −0.92, respectively) were found between open-field activity and defecation in recombinant-inbred strains descended from a cross of C57BL/6By and BALB/cBy strains. These correlations were found to be dependent on the level of illumination in the open-field test. They were statistically significant in a brightly illuminated open field but statistically insignificant in a dimly illuminated test situation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01066973
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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