ISSN:
0947-6539
Keywords:
amino acids
;
asymmetric synthesis
;
BNCT
;
carboranes
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Two α-amino acids containing the 1,2-dicarba-closo-dodecaborane (12) cage, namely, 5-(1,2-dicarba-closo-dodecaboran (12)-1-yl)-2-aminopentanoic acid (1) and 5-(2-methyl-1,2-dicarba-closo-dodecaboran (12)-1-yl)-2-aminopentanoic acid (2), were prepared by asymmetric synthesis (e.p. 〉 98%) by using the chiral glycine equivalent, imidazolidinone 3, introduced by Seebach, and Oppolzer's camphor-derived sultam derivative 4. The dextrorotatory enantiomers (sodium D line in methanol) of the amino acids 1 and 2 were both shown to have (S) configuration.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19950010707
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