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  • 1
    Electronic Resource
    Electronic Resource
    Effect of dietary chronic cadmium exposure on cell-mediated immune response in Rhesus monkeys (Macaca mulatta): role of calcium deficiency (1984)
    Springer
    Archives of toxicology 56 (1984), S. 128-131 
    Details
    ISSN: 1432-0738
    Keywords: Cadmium ; Calcium ; Monkey ; Cell-mediated immune response ; Lymphocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of Ca deficiency on the immunomodulatory effects of chronic Cd exposure for a period of 10 weeks in male Rhesus monkeys were assessed by the blastogenic capacity of peripheral blood lymphocytes (PBL) in response to T-cell mitogens, phytohemagglutinin (PHA), and concanavalin A (Con A). Calcium deficiency significantly decreased the blastogenic response to PHA (P〈0.01) and Con A (P〈0.05). Although Cd exposure in normal monkeys significantly increased the blastogenic response to Con A (P〈0.05), Cd exposure in Ca-deficient monkeys produced a further significant decrease in the blastogenic response to Con A (P〈0.001). Total and ionic Ca were also significantly decreased in plasma of Ca deficient monkeys exposed to Cd. It is possible that these two observations may be related to each other. Thus, it is important to assess the nutritional status of the host while evaluating the immunotoxicological effects of an environmental pollutant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00349085
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Interaction of bacterial acidic polysaccharide with cationic dyes (1993)
    Springer
    Colloid & polymer science 271 (1993), S. 1042-1048 
    Details
    ISSN: 1435-1536
    Keywords: Bacterial polymer ; cationic dye ; dye-polymer interaction ; metachromasy ; chromotropic property ; thermodynamic parameters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The interaction of acidic capsular polysaccharide isolated fromKlebsiella K26 with cationic dyes pinacyanol chloride, acridine orange and phenosafranin has been studied by spectral measurements. The polymer induces metachromasy in pinacyanol chloride dye, indicating a blue shift in the visibly absorption spectrum of the dye from 600 to 500 nm. The stoichiometry of polymer/dye in the metachromatic compound, thermodynamic parameters of interaction, and effects of different cosolvents on the stability of the complex have been studied. Spectrophotometric and spectrofluorometric properties of the interaction between the polymer and all three dyes are presented. The chromotropic property of the polymer has been established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00659293
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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