ISSN:
1432-1106
Keywords:
Cerebellum
;
Barbiturates
;
Unitary activity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In precollicular decerebrate cats, limb nerves have been stimulated and field potentials and unitary activity recorded from the cerebellar cortex. Doses of pentothal up to 8 mg/kg affect neither the activity evoked in the fast mossy fibre pathways, nor the size of the postsynaptic potentials in granule cells, but the axon discharge in these latter cells is clearly affected. With 4–8 mg/kg the axon discharge of granule cells is abolished and as a consequence Purkinje cells do not respond to the peripheral stimulation via the mossy fibres. In contrast the activity evoked through the climbing fibres is enhanced. This effect takes place at precerebellar level. Both the effects on the mossy fibre and climbing fibre pathways show a recovery in 15–60 min depending on the dose.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00234563
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