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Effects of Δ 9-Tetrahydrocannabinol and pentobarbital on a cortical response evoked during conditioning (1976)

Boyd, E. S. ; Boyd, E. H. ; Brown, L. E.

Springer

Psychopharmacology 47 (1976), S. 119-122

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ISSN: 1432-2072

Keywords: Frontal cortex ; Evoked activity ; Behavior ; Tetrahydrocannabinol ; Pentobarbital

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract A surface-negative wave, evoked by tone cues, appeared in monkey post-arcuate cortex as the monkey learned that the cue signaled the availability of reward. This evoked activity was depressed, concomitantly with changes in the animal's behavioral responding, by doses of Δ 9-tetrahydrocannabinol (Δ 9-Tetrahydrocannabinol-THC) as low as 0.032 mg/kg and of pentobarbital as low as 4 mg/kg. Pentobarbital tended to increase the latency of the evoked wave, an effect not seen with Δ 9-THC.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00428713

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