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  • 1
    Electronic Resource
    Electronic Resource
    Anti-Borrelia burgdorferi antibodies in patients with facial paralysis (1993)
    Springer
    European archives of oto-rhino-laryngology and head & neck 249 (1993), S. 488-491 
    Details
    ISSN: 1434-4726
    Keywords: Bell's palsy ; Lyme disease ; Borrelia burgdorferi ; Whole B. burgdorferi antigen ; Flagellum protein antigen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Ninety-eight patients with facial paralysis were studied by an indirect enzyme-linked immunosorbent assay (ELISA) employing two types of Borrelia burgdorferi antigen, namely sonic extract and flagellum protein of B. burgdorferi. IgG or IgM antibodies were detected by sonic extract ELISA in 22 (32.4%) of 68 patients with Bell's palsy, and in 2 (10.0%) of 20 patients with varicella-zoster virus infection. This difference was statistically significant (P〈0.05). A positive reaction was more frequent with the sonic extract antigen, while the positive rates were significantly increaesd in Bell's palsy patients with hyperglobulinemia (P〈0.05). IgM antibodies were also significantly more frequently observed in patients who developed Bell's palsy between October and March (P〈 0.05). Since none of the patients had a history suggestive of Lyme disease, some kind of non-specific reaction and certain undefined factors linked to a positive reaction against B. burgdorferi could be involved in Bell's palsy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00168862
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  • 2
    Electronic Resource
    Electronic Resource
    Intravascular hypercoagulability in patients with recent Bell's palsy (1994)
    Springer
    European archives of oto-rhino-laryngology and head & neck 251 (1994), S. 278-282 
    Details
    ISSN: 1434-4726
    Keywords: Bell's palsy ; Pathogenesis ; Thrombinantithrombin III complex ; α-2 plasmin inhibitor-plasmin complex ; Hypercoagulability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eighty-four patients were examined for blood coagulability during the acute phase of Bell's palsy. Abnormally high levels of thrombin-antithrombin III complex (TAT) and α-2 plasmin inhibitor-plasmin complex (PIC) were found, with these increases statistically significant. Values tended to be higher in patients within 3 days after occurrence of the palsy when compared to values in patients 4 days or more later. Abnormal TAT and PIC levels in the acute phase then tended to become normalized during the convalescent phase of the disease. These findings indicated that activation of intravascular coagulability had occurred, with patients entering a temporary clot-forming state. Among the several hypotheses for the etiology of Bell's palsy, our findings support a circulation disorder as an influential factor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00181885
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  • 3
    Electronic Resource
    Electronic Resource
    Studies in organic mass spectrometry - IV:For part III see Ref. 1. N-iminopyridinium betaines (1971)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 5 (1971), S. 935-938 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectra of N-iminopyridinium betaines, which have been generated within the ion source by pyrolysis of the corresponding hydrochlorides, have been compared with those of pyridine N-oxides.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210050804
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  • 4
    Electronic Resource
    Electronic Resource
    Studies in organic mass spectrometry - IIFor part I see Ref. 1 (1971)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 5 (1971), S. 389-396 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectra of various N-aryliminopyridinium and isoquinolinium betaines have been recorded. The most prominent fragmentation process of these compounds is N-N bond cleavage with the charge retention on both the pyridine and aryl fragments. An ortho-effect has been observed in the mass spectrum of N-o-nitrophenyliminopyridinium betaine (IXa).
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210050405
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  • 5
    Electronic Resource
    Electronic Resource
    Studies in organic mass spectrometry - V:For Part IV, see ref. 3. N-arylsulphonyliminopyridinium betaines (1971)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 5 (1971), S. 1383-1390 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectral fragmentation of N-arylsulphonyliminopyridinium betaines has been rationalized using high resolution mass spectrometry as well as deuterium labelling. The most characteristic features are a very facile N—S bond cleavage and skeletal rearrangements accompanied by the expulsion of SO2 from the molecular ion and the [M—1] ion to the corresponding ionized N-aryliminopyridinium betaines and azacarbazoles, respectively. The presence of methyl substituents at the α-position of the pyridine ring has a significant effect on the mode of the fragmentation.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210051205
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  • 6
    Electronic Resource
    Electronic Resource
    The mass spectra of N-acyliminopyridinium and isoquinolinium betaines (1971)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 5 (1971), S. 61-71 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The mass spectral fragmentation behaviour of N-acyliminopyridinium and isoquinolinium betaines has been investigated. Major fragmentations of the pyridinium betaines can be rationalized in terms of charge localization on the pyridinium nitrogen. The most prominent process is α-cleavage followed by loss of NCO to furnish a pyridine ion. The electron-impact induced fragmentation of N-benzoyliminopyridinium betaine (I) was compared with that of thermolysis. The completely analogous behaviour has been observed in the corresponding isoquinolinium betaines.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210050108
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