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  • Benzodiazepines  (5)
  • Hemodialysis  (3)
  • 1
    Digitale Medien
    Digitale Medien
    Blood plasma fluoride in haemodialysed patients
    Amsterdam : Elsevier
    Clinica Chimica Acta 156 (1986), S. 105-108 
    Details
    ISSN: 0009-8981
    Schlagwort(e): Fluoride ; Free-fluoride dialyzates ; Hemodialysis
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90185-3
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  • 2
    Digitale Medien
    Digitale Medien
    Pharmacokinetics of desferrioxamine and of its iron and aluminium chelates in patients on haemodialysis
    Amsterdam : Elsevier
    Clinica Chimica Acta 170 (1987), S. 331-338 
    Details
    ISSN: 0009-8981
    Schlagwort(e): Aluminoxamine ; Desferrioxamine ; Ferrioxamine ; Hemodialysis ; Pharmacokinetics
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(87)90144-6
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  • 3
    Digitale Medien
    Digitale Medien
    Increase in blood plasma levels of boron and strontium in hemodialyzed patients
    Amsterdam : Elsevier
    Clinica Chimica Acta 156 (1986), S. 315-320 
    Details
    ISSN: 0009-8981
    Schlagwort(e): Boron ; Hemodialysis ; ICP ; Strontium ; Trace elements
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0009-8981(86)90074-4
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  • 4
    Digitale Medien
    Digitale Medien
    Benzodiazepines and behavioral effects of reward (water) omission in the rat (1978)
    Springer
    Psychopharmacology 59 (1978), S. 95-100 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Frustrative nonreward ; Response suppression ; Over-responding ; Benzodiazepines ; Amobarbital ; Meprobamate ; Rats
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Two behaviors related to nonreward (omission of water in an enclosure where the rats were habituated to drink) were studied. The time spent licking the bottles during water omission and the time spent drinking during a subsequent 5-min drinking session (water available) were recorded. The drinking session was performed 30 min after the water-omission session. Rats subjected to water omission showed an enhanced drinking time that varied with the length of the water omission session, with the motivational state of the animals, and with the previous number of wateromission sessions. Diazepam, chlordiazepoxide, lorazepam, and meprobamate (i.p., 30 min before water omission), increased the time spent licking the empty bottles, but failed to abolish subsequently enhanced drinking. However, some of our data suggested that minor tranquilizers weakly reduced the increased drinking induced by nonreward, despite their direct stimulation on water drinking. It is proposed that either minor tranquilizers are devoid of general antifrustration activity or nonreward-induced frustration and nonreward-induced drive enhancement may not be correlated.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00428038
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  • 5
    Digitale Medien
    Digitale Medien
    Effets des anxiolytiques sur la prise de boisson en situation nouvelle et familière (1976)
    Springer
    Psychopharmacology 50 (1976), S. 41-45 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Water intake ; Benzodiazepines ; Phenobarbital ; Meprobamate ; Mecloqualone ; Rats and mice
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract In water-deprived rats and mice, animals trained to the test situation spent more time in drinking than naive animals (first exposure to the test situation). The time spent in drinking, either during 5 min or during 10 min was recorded. As compared to controls, benzodiazepines, phenobarbital, meprobamate, and mecloqualone increased drinking time whether the experiments were run on naive or on experienced animals [5 or 10 (in mice) and 9 (in rats) exposures in the test situation]. All drugs were injected i.p. 30 min before testing. This release of the drinking behavior was more pronounced during the last 5 min than during the first 5 min of the 10 min test session. These results suggest that: 1. The inhibition of water intake of naive animals as compared to trained rats and mice, could be related to some emotional factors elicited by the first exposure to an unknown situation. 2. The increase in drinking time induced by the antianxiety drugs in a novel and in a familiar situation seems difficult to correlate only with the antianxiety action of these compounds. 3. Antianxiety drugs could interfere with the regulatory mechanism of thirst.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00634152
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  • 6
    Digitale Medien
    Digitale Medien
    Effets du diazépam sur six modèles d'hyperactivité chez la souris (1975)
    Springer
    Psychopharmacology 45 (1975), S. 197-201 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Locomotor activity ; Diazepam ; Benzodiazepines ; Dexamphetamine ; Anticholinergics ; Mice
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Experiments were carried out in mice to investigate the influence of diazepam (DZP) on dexamphetamine, para-chloro-N-methylamphetamine (pCMA), cocaine, morphine, trihexyphenidyl or (in MAOIs pretreated) reserpine induced motor hyperactivity. The interaction of DZP with these hyperactivities in which probably different biochemical central mechanisms are involved allows to construct a profile of action of DZP and to approach its mechanism of action. The locomotor hyperactivities induced by dexamphetamine, pCMA, morphine, cocaine were not reduced by DZP even by doses which decrease spontaneous locomotor activity; low doses of DZP enhance the hyperactivity induced by these compounds. Those induced by trihexyphenidyle or by reserpine (after MAOI) were reduced by DZP at doses which produce no decrease in spontaneous motor activity. Inasmuch as DZP at low doses potentiates the effects of 4 different substances, the results can hardly be satisfactorily explained neither by an interference of the benzodiazepine on the metabolism of the drugs or by a depression of the anxiogenic action of dexamphetamine. Even though it may be difficult to relate the antagonism of DZP on trihexyphenidyl- or on reserpine- (after MAOI) induced motor hyperactivity to the suggested anticholinergic and dopaminergic actions of DZP, these effects may partly be involved in the increase in locomotor hyperactivity induced by dexamphetamine, morphine or cocaine. The observed effect of DZP on pCMA induced locomotor hyperactivity does not support a possible antiserotonine action often suggested to explain the effects of benzodiazepines in conflict situations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00429061
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  • 7
    Digitale Medien
    Digitale Medien
    Effets des anxiolytiques sur la prise de nourriture de rats et de souris placés en situation nouvelle ou familière (1975)
    Springer
    Psychopharmacology 45 (1975), S. 203-210 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Food intake ; Benzodiazepines ; Barbiturates ; Meprobamate ; Rats ; Mice
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Various minor tranquilizers (benzodiazepines, barbiturates and meprobamate) induced an increase in the food intake of rats or mice. Drugs were injected i.p. 30 min before testing and the amount of food consumed during 30 min was recorded. The enhanced food consumption occurred when the animals were in a novel situation, in a situation which they had previously experienced, or in their home cage, in which they were used to eating in the daytime within 30 min. Studies with two benzodiazepines showed this effect to be maximal between 10 to 30 min after injection and to disappear 4 hrs after injection. Moreover, minor tranquilizers reduce the latency before eating of rats and mice tested in a new situation. These results and the observation of anti-anxiety drugs-induced hyperphagia in satiated animals suggest that: 1. The enhanced food consumption of a non familiar food in a novel situation induced by the minor tranquilizers could hardly be related only to their anti-anxiety action. 2. The existence of some inhibitory controls (endogenous satiety in daytime or satiety after recent absorption) is not essential for the action of the minor tranquilizers. 3. An increased motivation and a disruption in the food related behavior could possibly be an explanation for all the observed effects.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00429062
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  • 8
    Digitale Medien
    Digitale Medien
    Comparing benzodiazepines using the staircase test in mice (1987)
    Springer
    Psychopharmacology 92 (1987), S. 106-109 
    Details
    ISSN: 1432-2072
    Schlagwort(e): Staircase test ; Exploration ; Locomotion ; Anxiolytics ; Sedation ; Benzodiazepines ; Therapeutic index ; mice
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Eleven benzodiazepines were evaluated in the staircase test in mice. The behavioural parameters measured were the number of steps climbed and the number of rears during a 3-min test. Climbing and to a lesser extent rears were enhanced at low doses, whereas both parameters, particularly rearing, were reduced at higher doses. The differential effects of the drugs on the two parameters were used to determine indices of anxiolytic efficacy for each drug where increases in climbing were taken to indicate the onset of anxiolytic activity and decreases in rearing the onset of sedative activity. The compounds could be ranked according to these indices in a manner which appears to reflect their therapeutic profile in man.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00215488
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