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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 95 (1988), S. 208-215 
    ISSN: 1432-2072
    Keywords: Lorazepam ; Benzodiazepines ; Human memory ; Attention ; Sedation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of three doses of lorazepam (0.5, 1.0 and 2.0 mg PO) on various aspects of memory, attention and sedation are described. Lorazepam produced dose-related deficits in verbal secondary memory, choice reaction time and a novel vigilance task. It also produced a dose-dependent increase in subjective sedation, and an enhancement of visual contrast sensitivity. These results are compared with those reported earlier using the muscarinic antagonist scopolamine, and discussed in relation to models of Alzheimer's disease.
    Type of Medium: Electronic Resource
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