ISSN:
1432-2072
Keywords:
Lorazepam
;
Benzodiazepines
;
Human memory
;
Attention
;
Sedation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The effects of three doses of lorazepam (0.5, 1.0 and 2.0 mg PO) on various aspects of memory, attention and sedation are described. Lorazepam produced dose-related deficits in verbal secondary memory, choice reaction time and a novel vigilance task. It also produced a dose-dependent increase in subjective sedation, and an enhancement of visual contrast sensitivity. These results are compared with those reported earlier using the muscarinic antagonist scopolamine, and discussed in relation to models of Alzheimer's disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00174511
Permalink