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  • Biochemistry and Biotechnology  (2)
  • Engineering  (1)
  • Polyhedra  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Mathematical programming 34 (1986), S. 48-61 
    ISSN: 1436-4646
    Keywords: Total Dual Integrality ; Hilbert Basis ; Polyhedra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract Edmonds and Giles introduced the class of box totally dual integral polyhedra as a generalization of submodular flow polyhedra. In this paper a geometric characterization of these polyhedra is given. This geometric result is used to show that each TDI defining system for a box TDI polyhedron is in fact a box TDI system, that the class of box TDI polyhedra is in co-NP and is closed under taking projections and dominants, that the class of box perfect graphs is in co-NP, and a result of Edmonds and Giles which is related to the facets of box TDI polyhdera.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 8 (1974), S. 27-43 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Body oriented co-ordinates are defined for three-dimensional regions bounded by six surfaces. From this definition of body oriented co-ordinates, two transformations are derived: 1Body oriented surface co-ordinates to the Cartesian co-ordinates, and2Body oriented co-ordinates for a three-dimensional region to Cartesian co-ordinates.With these transformations a mesh generator is developed based on the principle that the mesh required to describe a region will be calculated according to the placement of the discrete points that describe the boundary edges. This is accomplished with two versions of the mesh generator: the surface generator and the volume generator. The surface generator maps the four boundaries of the surface onto the four boundaries of a unit square. Next, the interior points for the surface mesh are established in the mapped space. Then, using the first transformation, the co-ordinates for the surface nodal points are calculated. Similarly, the volume generator maps the six surfaces of the body onto the surfaces of a unit cube, establishes the interior nodal points in the mapped space, and using the second transformation, calculates the co-ordinates for the interior nodal points.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Proteins: Structure, Function, and Genetics 22 (1995), S. 187-190 
    ISSN: 0887-3585
    Keywords: cytokine ; BCRF1 ; protein structure ; crystal seeding ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Crystals of recombinant human interleukin 10 have been grown from solutions of ammonium sulfate. The crystals are tetragonal, space group P41212 or P43212; the unit cell axes are a = 36.5 Å and c = 221.9 Å. There is the equivalent of one polypeptide chain in the asymmetric unit. The crystals are stable to X-rays and diffract to at least 2.5 Å resolution. © 1995 Wiley-Liss, Inc.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0887-3585
    Keywords: crystallization ; interferon-γ ; receptor complex ; purification ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: X-ray diffraction quality crystals have been obtained from a complex between interferon γ and the extracellular domain of its high-affinity cell surface receptor. The crystals were obtained from interferon γ/interferon γ receptor complexes purified by size exclusion chromatography. Diffraction quality crystals required analyzing these complex samples by isoelectric focusing gels to select purified complex fractions devoid of unbound interferon γ. These studies used interferon γ receptor engineered with an eight amino acid N-terminal deletion to eliminate heterogeneity generated due to proteolytic cleavage. In addition, the receptor was expressed in an E. coli secretion cell line which eliminated the need to refold the protein. Hexagonal crystals were grown from 1.6 M ammonium phosphate solutions and belong to a spacegroup of P6522 with unit cell dimensions a = 145.9 Å and c = 180.3 Å. These crystals diffract to at least 2.9 Å resolution when exposed to synchrotron radiation. SDS PAGE analysis of the crystals demonstrated that both interferon γ and the receptor were present. Analysis of the x-ray diffraction data revealed that the crystals contain complexes with a stoichiometry of 2:1 receptor: ligand within the crystallographic asymmetric unit and consist of approximately 55% solvent. © 1996 Wiley-Liss, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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