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Monte Carlo simulation of DNA electrophoresis (1989)

Batoulis, Jannis ; Pistoor, Norbert ; Kremer, Kurt ; [et al.]

Weinheim : Wiley-Blackwell

Electrophoresis 10 (1989), S. 442-446

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ISSN: 0173-0835

Keywords: Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Chemistry and Pharmacology

Notes: This paper describes an attempt to study the electrophoresis mobility of a DNA molecule in a gel by means of a Monte Carlo simulation. We find that the electrophoresis mobility μ can be well described by the empirical equation μ = κ1/N + κ2E2 with N being the number of monomers of the model chain and E being the applied field. For small E the data can merge into the linear response result μ = κ1/N. The paper also discusses necessary extensions of the present approach.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/elps.1150100522

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