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  • 1
    Electronic Resource
    Electronic Resource
    Effect of streptozotocin-induced diabetes on the handling of phosphate by the rat small intestine (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 10 (1992), S. 261-266 
    Details
    ISSN: 0263-6484
    Keywords: Enterocytes ; streptozotocin-induced diabetes ; Pi uptake ; Pi efflux ; brush-border membranes ; proteins ; alkaline phosphatase ; SDS-PAGE ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effect of chemically-induced diabetes on the handling of phosphate (Pi) by rat jejunal enterocytes has been investigated in the presence of a Na- or a choline-gradient. Pi uptake was significantly increased in both gradients. The Pi efflux rate constants for enterocytes from diabetic rats were similar to those of control rats. The effect of diabetes on both the protein and alkaline phosphatase isoenzymes of the rat small intestinal brush-border membranes was examined using SDS-PAGE. The patterns given by membranes from rats 14 days after the induction of diabetes were no different from those of controls.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290100409
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phosphate efflux from jejunal enterocytes of the rat: Effect of phosphate concentration gradient and pH (1992)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 10 (1992), S. 257-260 
    Details
    ISSN: 0263-6484
    Keywords: Enterocytes ; efflux rate constant ; Pi efflux ; intracellular and extracellular Pi concentration ; extracellular pH ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effect of variation in the intracellular and extracellular phosphate concentration on the Pi efflux across the basolateral membrane of pre-loaded enterocytes has been examined. Efflux rate constants for Pi fell from 0·89 h-1 to 0·68 h-1 as the extracellular Pi concentration was increased from 0·5 mM to 5 mM. As the intracellular Pi concentration was raised from 0·5 to 3 mM the rate constant dropped from 0·95 h-1 to 0·77 h-1. The findings are indicative of the presence of Pi-specific transporter at the basolateral membrane. The efflux rate constant of Pi at pH 7·1 was higher than that at pH 7·4 suggesting that the Pi flux across the basolateral membrane of enterocytes follows a similar pattern towards pH changes as do fluxes across the brush-border membrane.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290100408
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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