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  • 1990-1994  (2)
  • Biomechanics  (1)
  • Neoantigens  (1)
  • 1
    Electronic Resource
    Electronic Resource
    No evidence for neoantigens in human plasma after photochemical virus inactivation (1992)
    Springer
    Annals of hematology 65 (1992), S. 224-228 
    Details
    ISSN: 1432-0584
    Keywords: Photochemical virus inactivation ; Phenothiazine dyes ; Human fresh plasma ; Neoantigens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Photodynamic virus inactivation of human fresh plasma mediated by visible light in the presence of the phenothiazine dyes methylene blue or toluidine blue was investigated to determine whether it influences functional, structural, and immunological properties of plasma proteins. The activities of the coagulation factors I, VIII, IX, X, and XI were affected to a certain degree, while those of most other plasma proteins were not. The elution profiles obtained by ion exchange chromatography of untreated and photodynamically treated plasma were almost identical. Using a number of antisera against human plasma and single plasma proteins, different immunochemical techniques revealed identical patterns for untreated and treated plasma. Thus, there was no indication that the photodynamic virus inactivation procedure applied considerably influences the properties of plasma proteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01703949
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A universal spine tester for in vitro experiments with muscle force simulation (1994)
    Springer
    European spine journal 3 (1994), S. 91-97 
    Details
    ISSN: 1432-0932
    Keywords: Biomechanics ; Spine tester ; Spinal stability ; Muscle simulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report a new apparatus to determine the quasistatic, three-dimensional, load-displacement characteristics of spines including muscle forces. The loading frame can be adapted to mono- and polysegmental specimens from the lumbar or cervical spine as well as to entire spines. Three force and three moment components can be applied in either direction individually or in combination with no constraint on the resulting motion; the loads can be applied at user-chosen rates of application and release with continuous recording of displacements, so as to study either creep or relaxation. The loads and displacement-measuring devices are computer-controlled. Thus, this testing device provides a tool for many kinds of stability tests and for basic research of spine biomechanics. A first experiment shows that the application of muscle forces significantly affects the load-deformation characteristics and intradiscal pressure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02221446
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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