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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Neuroradiology 40 (1998), S. 477-482 
    ISSN: 1432-1920
    Schlagwort(e): Key words Brain ; anatomy ; Brain ; white matter ; Brain ; oedema ; Magnetic resonance imaging
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract MRI was obtained in eight normal volunteers and seven patients with brain oedema around the trigone. In addition to the conventional sequences, diffusion-weighted and intravoxel-incoherent-motion images using motion-proving anteroposterior and/or lateral direction gradients were obtained to show the white matter pathways better. Coronal proton-density-weighted images showed three thin relatively high-intensity layers in addition to the tapetum and the internal and external sagittal strata. Although they have not been confirmed anatomically, the thin layer between the internal and the external sagittal strata was corroborated by diffusion-weighted and intravoxel-incoherent-motion images, and by characteristics of the spread of oedema into the sagittal stratum. We propose that this layer be named the central sagittal lamina. The other two layers medial and lateral to the sagittal stratum were outside, but in contact with the medial and lateral parts of the sagittal stratum, respectively. We provisionally named them medial and lateral sagittal laminae; they were not evident on any other images. The low-intensity layer on T2-weighting was the internal sagittal stratum. The optic radiation, comprising the external sagittal stratum, appeared as an intermediate to slightly high-intensity layer on T2-weighted images and a low-intensity layer on T1-weighted images as did the corticospinal tract in the posterior internal capsule.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Neuroradiology 40 (1998), S. 27-31 
    ISSN: 1432-1920
    Schlagwort(e): Key words Brain ; anatomy ; Magnetic resonance imaging ; threedimensional ; Virchow-Robin spaces
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We performed a histopathological study of two human brains to look at dilated Virchow-Robin (V-R) spaces in the anterior perforated substance and putamen. We measured the diameter of 74 arteries in 54 dilated V-R spaces. In 28 patients without neurological deficits we ascertained the characteristic location of dilated V-R spaces in the anterior perforated substance and basal ganglia on MRI, measuring the distance from 64 foci of cerebrospinal fluid signal intensity to the centre of the mamillary body on 1 mm thick images. In the histopathological study, the mean diameter of the arteries was 39.0 ± 36.0 μm. Dilatation of the V-R space was observed from the end of the indentation of the pial membrane towards the brain surface along the perforating artery. In the MR images, the mean distance from the dilated V-R space to the mamillary body was 10.0 ± 4.5 mm. The V-R space was confined to a fixed level in the lower part of the basal ganglia, and not found near the brain surface.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Molecular genetics and genomics 251 (1996), S. 60-68 
    ISSN: 1617-4623
    Schlagwort(e): Idiomorph ; DNA binding ; Mating type ; Bipolaris sacchari ; Cochliobolus heterostrophus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract The availability of cloned genes that control sexual reproduction (mating type genes) in higher fungi has allowed us to consider the causes of failure to mate in asexual fungi. We report here that the asexual fungusBipolaris sacchari has a homolog of theMAT-2 gene of its sexual ascomycete relativeCochliobolus heterostrophus. TheB. sacchari MAT-2 sequence is highly similar to that ofC. heterostrophus MAT-2 and, in fact, functions in transgenicC. heterostrophus. Thus, the asexual nature ofB. sacchari is not due to absence or mutation ofMAT. When either of theC. heterostrophus MAT genes was transformed intoB. sacchari, the recipient could neither self nor cross with otherB. sacchari strains, in contrast to transgenicC. heterostrophus strains which can do both. Persistent asexuality ofB. sacchari, in spite of the presence of complementary functionalMAT genes, suggests that this fungus lacks genes other thanMAT which are essential for mating. Notably, the transgenicB. sacchari strains were sometimes able to initiate, but not complete, sexual development in interspecific pairings withC. heterostrophus. Transcript analysis showed that theB. sacchari MAT-2 gene is expressed in transgenicC. heterostrophus and that theC. heterostrophus MAT genes are expressed in transgenicB. sacchari. No transcript of the nativeB. sacchari MAT-2 gene was detected under any growth condition tested.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Molecular genetics and genomics 251 (1996), S. 60-68 
    ISSN: 1617-4623
    Schlagwort(e): Key words Idiomorph ; DNA binding ; Mating type ; Bipolaris sacchari ; Cochliobolus heterostrophus
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  The availability of cloned genes that control sexual reproducti on (mating type genes) in higher fungi has allowed us to consider the causes of failure to mate in asexual fungi. We report here that the asexual fungus Bipolaris sacchari has a homolog of the MAT-2 gene of its sexual ascomycete relative Cochliobolus heterostrophus. The B. sacchari MAT-2 sequence is highly similar to that of C. heterostrophus MAT-2 and, in fact, functions in transgenic C. heterostrophus. Thus, the asexual nature of B. sacchari is not due to absence or mutation of MAT. When either of the C. heterostrophus MAT genes was transformed into B. sacchari, the recipient could neither self nor cross with other B. sacchari strains, in contrast to transgenic C. heterostrophus strains which can do both. Persistent asexuality of B. sacchari, in spite of the presence of complementary functional MAT genes, suggests that this fungus lacks genes other than MAT which are essential for mating. Notably, the transgenic B. sacchari strains were sometimes able to initiate, but not complete, sexual development in interspecific pairings with C. heterostrophus. Transcript analysis showed that the B. sacchari MAT-2 gene is expressed in transgenic C. heterostrophus and that the C. heterostrophus MAT genes are expressed in transgenic B. sacchari. No transcript of the native B. sacchari MAT-2 gene was detected under any growth condition tested.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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