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  • 1
    Electronic Resource
    Electronic Resource
    Reactions with 2-aminonicotinic acid, I Some 8-aza analogs of quinazolinones and derived tricyclic compounds (1983)
    Springer
    Monatshefte für Chemie 114 (1983), S. 1197-1203 
    Details
    ISSN: 1434-4475
    Keywords: 10-Aza-5,6-dihydro-3-hydroxy-5-(2-methylphenyl)-2-substituted-1H-pyrido[1,2-a]quinazoline-1,6-diones ; Bis-2,4,6-trichlorophenyl malonates ; 3H-Pyrido[2,3-d]pyrimidin-4-ones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Die Fusion von 2-Acetamidonikotinsäure mito-Toluidin,p-Bromanilin odero-Chloranilin ergab die entsprechenden 3-Aryl-2-methyl-pyrido[2,3-d]pyrimidin-4(3H)-one (4) und die 8-Aza-Analogen von 3-Aryl-2-methyl-4-chinazolinonen zusammen mit 2-Aminonikotinsäure. 2-Methyl-3-(2-methylphenyl)-pyrido[2,3-d]pyrimidin-4(3H)-on (4a), das 8-Aza-Analog von Methaqualon, wurde mittels Kondensation mit einigen aromatischen Aldehyden zu den 2-substituierten Styryl-Derivaten6 umgesetzt. Die Reaktion mit monosubstituierten Bis-2,4,6-trichlorphenylmalonaten ergab tricyclische 10-Aza-5,6-dihydro-3-hydroxy-5-(2-methylphenyl)-2-substituierte 1H-Pyrido[1,2-a]quinazolin-1,6-dione (8).
    Notes: Abstract The fusion of 2-acetamidonicotinic acid witho-toluidine,p-bromoaniline oro-chloroaniline afforded the corresponding 3-aryl-2-methyl-pyrido-[2,3-d]pyrimidin-4(3H)-ones (4), the 8-aza analogs of 3-aryl-2-methyl-4-quinazolinones, alongside 2-aminonicotinic acid. 2-Methyl-3-2(2-methylphenyl)-pyrido[2,3-d]pyrimidin-4(3H)-one (4a), the 8-aza analog of methaqualone, was converted to the 2-substituted styryl derivatives6 by condensation with some aromatic aldehydes and to the tricyclic system, 10-aza-5,6-dihydro-3-hydroxy-5-(2-methylphenyl)-2-substituted-1H-pyrido [1,2-a] quinazoline-1,6-diones (8) by reaction with monosubstituted bis-2,4,6-trichlorophenyl malonates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799933
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  • 2
    Electronic Resource
    Electronic Resource
    Reactions with pyrrolidine-2,4-diones, I. New synthesis of pyrano[2,3-c]pyrrole and pyrrolo[3,4-b]pyridine systems (1982)
    Springer
    Monatshefte für Chemie 113 (1982), S. 475-484 
    Details
    ISSN: 1434-4475
    Keywords: Bis-2,4,6-trichlorophenyl malonates ; 1,5-Diaryl-1,5-dihydro-4-amino-2H-pyrrol-2-ones ; 1,5-Diarylpyrrolidine-2,4-diones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Die Synthese einiger substituierter 4-Hydroxy-2,5,6,7-tetrahydro-pyrano[2,3-c]pyrrol-2,5-dione (5) und 4-Hydroxy-1,2,6,7-tetrahydro-5H-pyrrolo[3,4-b]pyridin-2,5-dione (6) gelingt durch Reaktion von 1,5-Diaryl-pyrrolidin-2,4-dion (1) bzw. 1,5-diaryl-1,5-dihydro-4-amino-2H-pyrrol-2-on (3) mit Malonsäure-bis-2,4,6-trichlorphenylester (4).
    Notes: Abstract The synthesis of some substituted 4-hydroxy-2,5,6,7-tetrahydro-pyrano[2,3-c]pyrrole-2,5-diones (5) and 4-hydroxy-1,2,6,7-tetrahydro-5H-pyrrolo[3,4-b]pyridine-2,5-diones (6) by reacting 1,5-diaryl-pyrrolidine-2,4-diones (1) and 1,5-diaryl-1,5-dihydro-4-amino-2H-pyrrol-2-ones (3) with bis-2,4,6-trichlorophenyl malonates (4) is described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00799923
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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