Electronic Resource
Springer
Acta neuropathologica
54 (1981), S. 149-152
ISSN:
1432-0533
Keywords:
Experimental allergic encephalomyelitis
;
Blood
;
Brain barrier
;
Fibrinogen
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Classical acute allergic encephalomyelitis (EAE) was provoked in Lewis rats with bovine spinal cord (BWM) in complete Freund's adjuvant (CFA). An efficient immunohistologic technique (peroxidase-antiperoxidase (PAP)) was used to trace exsudates of fibrinogen and immunoglobulin as well as their coexistence with cellular infiltrates and clinical signs. Exsudation was restricted to the vessels exhibiting cellular infiltrates. The findings do not lend support to the assumption that exsudation of circulating factors is the initial local event in EAE. It also remains open, whether the exsudation of fibrinogen and gamma globulin are responsible for the clinical symptoms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00689408
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