ISSN:
1432-0533
Keywords:
Canine neuronal ceroidosis
;
Blue Heeler dog
;
Autofluorescent intraneuronal granules
;
Pleomorphic membranogranular cytosomes
;
Central nervous system neurons
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Neuronal ceroidosis was observed in an 18-month-old male Blue Heeler dog which was euthanized after showing a progressive gait and behavior abnormality, depression, paresthesia, and vision deterioration. The brain was slightly atrophic. Histopathology revealed autofluorescent, periodic acid-Schiff, luxol fast blue, and oil red O-positive intracytoplasmic granules in the neurons of the brain and spinal cord. There was a moderate diffuse reduction in the number of cerebellar and cerebrocortical neurons. Ultrastructurally, these neuronal cytosomes were diverse with preponderance of membranous profiles and granular matrix.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00687053
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