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  • 1
    Electronic Resource
    Electronic Resource
    Analysis of the angiographic findings in cases of childhood moyamoya disease (1988)
    Springer
    Neuroradiology 30 (1988), S. 111-119 
    Details
    ISSN: 1432-1920
    Keywords: Childhood moyamoya disease ; Cerebral angiography ; Stenosis ; Collateral pathways ; Aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebral angiograms of 34 patients with childhood moyamoya disease have been analysed, this analysis having revealed the following findings. The blood flow to abnormal net-like vessels (ANV) in the base of the brain is mainly supplied from the internal carotid artery (ICA) in the early stage of this disease. In a later stage, however, the blood supply is mainly from the posterior cerebral artery (PCA). Though, no remarkable change was found in the volumes of ANV from the early to later stages of the disease, the leptomeningeal collaterals, the most prominent anastomoses in moyamoya disease, had a tendency to decrease during the later stage with the development of PCA stenosis. Eighteen occlusive PCA lesions were found in the proximal portion of the PCA in eight cases (44%), and in the distal in nine cases (50%). The incidence of aneurysm (1.5%) and intracranial bleeding was low as compared to cases of adult moyamoya disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395611
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Childhood moyamoya disease before and after encephalo-duro-arterio-synangiosis: an angiographic study (1992)
    Springer
    Neuroradiology 34 (1992), S. 318-322 
    Details
    ISSN: 1432-1920
    Keywords: Childhood moyamoya disease ; Encephalo-duro-arterio-synangiosis ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Encephalo-duro-arterio-synangiosis (EDAS) is a new surgical operation for childhood moyamoya disease, and its effects have been studied by comparing pre-and postoperative angiograms in 27 patients. The development of collaterals from the external carotid arterial system into the territory of the middle cerebral artery was excellent in 16 of 54 cerebral hemispheres after EDAS, good in 25, and poor in 13. The development of collaterals after EDAS increased as the stenotic process in the internal carotid artery on preoperative angiograms increased except in the most advanced cases, where it seemed to decrease in comparison with the group with middle grade stenosis. After EDAS, not only the superficial temporal artery, but also the adjacent middle meningeal artery participated in forming collateral pathways. Furthermore, decrease of abnormal net-like vessels was observed when there was good to excellent development of collateral vessels. Stenotic lesions in the internal carotid and posterior cerebral arteries were often seen to progress, indicative of the rapidly progressive nature of childhood moyamoya disease. These results appear to suggest that EDAS should be performed as early as possible in childhood moyamoya disease before the occurrence of an irreversible ischaemic state and/or permanent neurological defects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588191
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Moyamoya disease: diagnostic accuracy of MRI (1995)
    Springer
    Neuroradiology 37 (1995), S. 356-361 
    Details
    ISSN: 1432-1920
    Keywords: Moyamoya disease ; Magnetic resonance imaging ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our purpose was to evaluate the diagnostic accuracy of MRI in moyamoya disease. We studied 30 patients with this disease, comparing MRI and angiographic findings. The diagnostic value of MRI was evaluated for occlusive lesions, collateral vessels, and parenchymal lesions. In all patients bilateral occlusion or stenosis of the supraclinoid internal carotid artery and proximal anterior and middle cerebral arteries was clearly shown by MRI, and staging of the extent of occlusion agreed with angiographic staging in 44 (73%) of 60 arteries. MRI, particularly coronal images, clearly showed basal cerebral moyamoya vessels in 54 hemispheres, and 45 of a total of 71 large leptomeningeal and transdural collateral vessels were identified. MRI also showed parenchymal lesions in 48 (80%) hemispheres, and the extent of occlusion in the anterior and posterior circulations respectively correlated with white matter and cortical and/or subcortical infarcts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588011
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Moyamoya disease: diagnostic accuracy of MRI (1995)
    Springer
    Neuroradiology 37 (1995), S. 356-361 
    Details
    ISSN: 1432-1920
    Keywords: Key words Moyamoya disease ; Magnetic resonance imaging ; Cerebral angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our purpose was to evaluate the diagnostic accuracy of MRI in moyamoya disease. We studied 30 patients with this disease, comparing MRI and angiographic findings. The diagnostic value of MRI was evaluated for occlusive lesions, collateral vessels, and parenchymal lesions. In all patients bilateral occlusion or stenosis of the supraclinoid internal carotid artery and proximal anterior and middle cerebral arteries was clearly shown by MRI, and staging of the extent of occlusion agreed with angiographic staging in 44 (73 %) of 60 arteries. MRI, particularly coronal images, clearly showed basal cerebral moyamoya vessels in 54 hemispheres, and 45 of a total of 71 large leptomeningeal and transdural collateral vessels were identified. MRI also showed parenchymal lesions in 48 (80 %) hemispheres, and the extent of occlusion in the anterior and posterior circulations respectively correlated with white matter and cortical and/or subcortical infarcts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588011
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Spectroscopic characterization of native and Co(II)-substituted zucchini mavicyanin (1997)
    Springer
    JBIC 2 (1997), S. 177-181 
    Details
    ISSN: 1432-1327
    Keywords: Key words Mavicyanin ; Blue copper protein ; Cobalt(II) substitution ; Magnetic circular dichroism spectrum ; Resonance Raman spectrum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract  Mavicyanin from zucchini peelings has been characterized by electronic absorption, circular dichroism (CD), magnetic circular dichroism (MCD), resonance Raman (RR), and electron paramagnetic resonance (EPR) spectra. The electronic absorption, CD, MCD, and EPR spectra are appreciably similar to those of stellacyanin from lacquer, in which the tetrahedral Cu center has a donor set composed of four amino acid residues [2 histidine (His), cysteine (Cys), and glutamine (Gln)]. Under neutral conditions, mavicyanin and stellacyanin show intense blue bands at 599 and 604 nm, respectively. However, the RR spectrum of mavicyanin between 300 and 450 cm–1, which is believed to originate from the predominant Cu–S stretching vibration, is remarkably different from that of stellacyanin. This might be due to a slight distortion of the tetrahedral Cu(II) center toward tetragonal geometry in mavicyanin. Moreover, the d–d transition bands of Co(II)-substituted mavicyanin are slightly blue-shifted compared with those of Co(II)-substituted stellacyanin. This finding also suggests a difference in distortion between these tetrahedral Co(II) centers in spite of the same donor sets.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007750050122
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Spectroscopic and electrochemical properties of two azurins (Az-iso1 and Az-iso2) from the obligate methylotroph Methylomonas sp. strain J and the structure of novel Az-iso2 (1999)
    Springer
    JBIC 4 (1999), S. 749-758 
    Details
    ISSN: 1432-1327
    Keywords: Azurin ; Methylamine dehydrogenase ; Blue copper protein ; Obligate methylotroph ; X-ray crystal structure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Methylomonas sp. strain J gives rise to two azurins (Az-iso1 and Az-iso2) with methylamine dehydrogenase (MADH-Mj). The intense blue bands characteristic of Az-iso1 and Az-iso2 are observed at 621 and 616 nm in the visible absorption spectra respectively, being revealed at 620−630 nm in those of usual azurins. The EPR signal of Az-iso1, similar to usual azurins, shows axial symmetry, while the axial EPR signal of Az-iso2 involves a slightly rhombic character. The half-wave potentials (E 1/2) of the two azurins and the intermolecular electron-transfer rate constants (k ET) from MADH-Mj to each azurin were determined by cyclic voltammetry. The E 1/2 values of Az-iso1 and Az-iso2 are +321 and +278 mV vs NHE at pH 7.0, respectively. The k ET value of Az-iso2 is larger than that of Az-iso1 by a factor of 5. However, the electron-transfer rate of Az-iso2 is interestingly slower than those of the azurins from a denitrifying bacterium, Alcaligenes xylosoxidans NCIB 11015, and the amicyanin from a different methylotroph, Methylobacterium extorquens AM1. The structure of Az-iso2 has been determined and refined against 1.6 Å X-ray diffraction data. The whole structure of Az-iso2 is quite similar to those of azurins reported already. The Cu(II) site of Az-iso2 is a distorted trigonal bipyramidal geometry like those of other azurins, but some of the Cu-ligand distances and ligand-Cu-ligand bond angle parameters are slightly different. These findings suggest that Az-iso2 is a novel azurin and perhaps functions as an electron acceptor for MADH.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00010653
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