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  • 1
    ISSN: 1432-0827
    Keywords: Bone mineralization ; Body composition ; Children ; DXA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Normative values for total body bone mineral content (TBBM) and total body bone mineral density (TBMD) were derived from measurements on 234 children 8–16 years of age. In addition, bone mineral content (BMC) and bone mineral density (BMD) values for selected regions of interest and soft tissue (bone free lean and fat) for the total body are presented. Bone mineral and soft tissue values were determined by dual energy X-ray absorptiometry (DXA) using a Hologic QDR-2000 in the array mode. Results of a stepwise multiple regression analysis revealed a significant correlation between bone-free lean tissue (BFLT) and BMD (r2 = 0.80) in girls. Adding age to the equation accounted for an additional 2% of the variance (P 〈 0.05) and height accounted for another 1% of the variance (P 〈 0.05). Body weight and fat tissue (FT) did not account for any additional variance. In boys BFLT correlated significantly with BMD (r2 = 0.75;P 〈 0.05); none of the other predictor variables accounted for additional variance. No significant differences were found in TBBM or TBMD between boys and girls at any age. There was a significant overall gender effect for only three regions of interest. Boys had greater BMC in the head region and had greater BMD in the upper limbs, but post hoc analysis revealed no significant differences for any specific age groups. Girls had greater overall BMD in the pelvis, but this difference was only significant at the 15–6-year age group. The changes in BFLT and FT over the age ranges were consistent with the growth literature. The normative values can be applied to the assessment of children and adolescents with health problems that may impact on the skeleton as well as to research studies investigating bone mineral development in children.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-3297
    Keywords: open-field behavior ; genetic, correlation ; CXB recombinant-inbred strains ; illumination conditions ; C57BL/6By mice ; BALB/cBy mice ; BALB/cJ mice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Psychology
    Notes: Abstract Confirming previous investigations involving descendants of C57BL/6J and BALB/cJ mouse strains, significant phenotypic, environmental, and genetic correlations (r=−0.53, −0.24, −0.92, respectively) were found between open-field activity and defecation in recombinant-inbred strains descended from a cross of C57BL/6By and BALB/cBy strains. These correlations were found to be dependent on the level of illumination in the open-field test. They were statistically significant in a brightly illuminated open field but statistically insignificant in a dimly illuminated test situation.
    Type of Medium: Electronic Resource
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