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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 226 (1981), S. 63-71 
    ISSN: 1432-1459
    Keywords: Sleep disorder ; EEG ; Body temperature ; Circadian rhythm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Ein zwölf Jahre alter Junge, der seit seinem achten Monat an Enzephalopathie litt, zeigte einen verlängerten Schlaf-Wach-Zyklus mit einer Dauer von 10–15 Tagen. Seine Körpertemperatur folgte dabei einem circadianen Rhythmus, aus dem geschlossen werden kann, daß einige normale circadianen Oszillatoren intakt waren. Dieser lange Schlaf-Wach-Zyklus konnte weder durch Gaben von Methylphenydat noch durch heftiges Wecken gestört werden, woraus man schließen kann, daß der Zyklus nicht dieselben Eigenschaften besitzt wie andere Rhythmen und die 10–15-tägige Periode des Schlafens und Wachens wahrscheinlich durch Mechanismen kontrolliert werden, die sich sehr von denen unterscheiden, welche das Verhalten im Normalzustand steuern. Das Datenmaterial belegt das Vorhandensein multipler Schwingungsrhythmen beim Menschen.
    Notes: Summary A severely brain-damaged boy of 12 years had a prolonged sleep-wakefulness cycle of 10–15 days' duration. His body temperature followed a circadian rhythm, suggesting that some normal circadian oscillators were intact. The long sleep-wakefulness cycle could not be influenced by either methylphenidate administration or enforced wakefulness, which suggests that the cycle did not have the same properties as other rhythms, and the 10–15-day periods of sleep-wakefulness were probably controlled by mechanisms different from those operating in normal state. The case shows that there are multiple oscillating mechanisms in the control of different rhythms in humans.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neurology 233 (1986), S. 274-282 
    ISSN: 1432-1459
    Keywords: Circadian rhythms ; Sleep-wakefulness ; Body temperature ; Blood cortisol ; Brain-damaged children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twelve patients aged 3–14 years with severe brain damage of prenatal, perinatal or postnatal origin were studied for 2–4 days regarding the circadian rhythms of sleep and wakefulness, body temperature and blood cortisol levels. Six patients had developed a disorder in the circadian rhythm of sleep and wakefulness. The circadian rhythm of body temperature was maintained in 11 of the patients and was little disturbed compared to those of sleep and wakefulness and cortisol levels. The three overt rhythms of circadian activity were not necessarily disturbed simultaneously, which does not contradict the multiple oscillatory theory of the human timekeeping system. CT findings suggested that the brain-stem plays a more important role than the cerebral hemispheres in the regulation of human circadian rhythms.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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