ISSN:
1573-7225
Schlagwort(e):
Breast cancer
;
breast pathology
;
histologic classification
;
hormone receptors
;
males
;
United States
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Medizin
Notizen:
Histologic slides from 282 incident cases of breast cancer in men, that were identified in 10 population-based cancer registries in the United States, were reviewed by a single pathologist. Breast cancer more often presented in the noninvasive stage in men (10.8 percent of all cases) than would be expected among women. All noninvasive carcinomas were of the ductal type. Of invasive carcinomas, compared with women, men had smaller proportions of lobular and mucinous types and larger proportions of ductal and papillary types and Paget's disease. No case of tubular or medullary carcinoma was seen. The breast in men is composed only of ducts and normally contains no lobules, and the histologic types of breast carcinomas that predominate in men are likely of ductal origin. Estrogen and progesterone receptors were present in 86.7 percent and 76.3 percent of invasive carcinomas, respectively, which are higher proportions than would be expected among women. Also, unlike findings in women, receptor content was not associated with patient age at diagnosis.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00053155
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