ISSN:
1435-1463
Keywords:
Buspirone
;
5-HT1A receptor
;
DA2 receptor
;
body temperature
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Buspirone, a putative serotonin (5-HT)1A partial agonist, did not produce hypothermia in 17 normal volunteers in a placebo controlled, single blind study. Thus, buspirone may be a weaker agonist at those 5-HT1A receptors which mediate hypothermia compared to ipsapirone or gepirone, two other 5-HT1A partial agonists which have been reported to produce hypothermia by a 5-HT1A-mediated mechanism.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01250377
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