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  • 1
    ISSN: 1432-1238
    Keywords: Alcoholics ; APACHE ; TISS ; Mortality ; ICU
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To study whether critically ill alcoholics were more sick and had a worse outcome than other patients treated in the intensive care unit, data were collected during the initial 24 h on 216 consecutive patients admitted to an intensive care unit. Twentysix patients (12%) met the criteria for alcohol abuse. The patients' chronic health 6 months prior to admission and the extent of physiological derangement (Acute Physiology Score and Chronic Health Evaluation (APACHE)) were recorded just as the type and amount of treatment (Therapeutic Intervention Scoring System (TISS)). Alcoholics were found to be significantly more sick and had a higher mortality (50% compared to 26%) than other critically ill patients. However, when analyzing the TISS points, no difference was found between the two groups. All survivors were, every third month up to 1 year after admission, asked to fill in a questionnaire indicating their level of activity. No differences were found between the two groups 1 year after admission, but the alcoholics had lost more time due to death. It is concluded that studies with larger number of patients will reveal whether alcogolics constitute a special category of patients with a different prognosis than other ICU patients.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of atmospheric chemistry 14 (1992), S. 95-108 
    ISSN: 1573-0662
    Keywords: Products ; mechanism ; NO3 ; gas phase ; CH3SCH3 ; CD3SCD3 ; CH3SH ; CH3SSCH3 ; isotope effect ; air ; troposphere
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Geosciences
    Notes: Abstract Products and mechanisms of the reaction between the nitrate radical (NO3) and three of the most abundant reduced organic sulphur compounds in the atmosphere (CH3SCH3, CH3SH and CH3SSCH3), have been studied in a 480 L reaction chamber using in situ FT-IR and ion chromatography as analytical techniques. In the three reactions, methanesulphonic acid was found to be the most abundant sulphur containing product. In addition the stable products SO2, H2SO4, CH2O, and CH3ONO2 were identified and quantified and thionitric acid-S-methyl ester (CH3SNO2) was observed in the i.r. spectrum from all of the three reactions. Deuterated dimethylsulphide (CD3SCD3) showed an isotope effect on the reaction Deuterated dimethylsulphide (CD3SCD3) showed an isotope effect on the reaction rate constant (kH/kD) of 3.8±0.6, indicating that hydrogen abstraction is the first step in the NO3+CH3SCH3 reaction, probably after the formation of an inital adduct. Based on the products and intermediates identified, reaction mechanisms are proposed for the three reactions.
    Type of Medium: Electronic Resource
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