ISSN:
1432-0568
Keywords:
Nucleus basalis Meynert
;
Calcium-ions
;
Vitamin D
;
Calbindin-D 28k
;
Neurodegenerative disorders
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The neurons of the monkey basal nucleus of Meynert are shown to contain a protein indistinguishable from the chicken intestinal 28kd vitamin D-dependent calcium-binding protein (Calbindin-D 28k; CBP). CBP is thought to shuttle and buffer Ca++-ions, thus regulating the intracellular calcium distribution and concentration. Our observation may engender interest in searching for the role of Vitamin D-metabolites, the CBP and calcium-ions in the physiology and pathology of nucleus basalis Meynert neurons.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00316296
Permalink