ISSN:
1612-1112
Keywords:
Miniaturized HPLC
;
Post-column reaction detection
;
Catecholamines
;
Packed-bed reactors
;
Non-segmented open-tubular reactors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The use of non-segmented flow, post-column reaction detection is evaluated for use with miniaturized HPLC. Non-segmented open-tubular reactors with internal diameters 0.1 mm to 0.25 mm and packed-bed reactors with internal diameters of 1 mm, filled with 5 and 10 μm particles are evaluated theoretically and experimentally with respect to band broadening and pressure drop characteristics. An integrated system consisting of miniaturized HPLC (1 mm i. d.) columns and compatible hardware is described. An example of the separation of catecholamines is given.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02271034
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