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  • 1985-1989  (2)
  • Brain tumor  (1)
  • Central caudal artery  (1)
  • 1
    ISSN: 1432-0533
    Schlagwort(e): Rat ; ENU ; Brain tumor ; Anti-Leu 7 ; GFAP
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary To clarify the chronologic changes in the cellular morphology of ENU-induced rat brain tumors, microtumors in the early stage were examined ummunohistochemically in comparison with macrotumors in the advanced stage. The tumor cells composing microtumors were negative for glial fibrillary acidic protein (GFAP), a specific marker of astrocylic cells, and Leu 7, a marker of oligodendrocytes, while cells of macrotumors were positive for either GFAP or Leu 7, showing characteristics of mature glial cells. The results suggested that the small round cells in the early devolopmental stage, generally thought to resemble mature oligodendrocytes, are not differentiated oligodendrocytes or astrocytes.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Medical & biological engineering & computing 25 (1987), S. 386-390 
    ISSN: 1741-0444
    Schlagwort(e): Central caudal artery ; Electrical impedance plethysmography ; Electromagnetic flowmetry ; Peripheral blood flow ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract The impedance Z, the derivative of Z with respect to time t, dZ/dt, and blood flow F have been measured simultaneously in the central caudal artery of a series of anaesthetised rats. The results of the experiments were expressed in the relationship derived from the Windkessel theory where f(t)=adz(t)/dt+βz(t), in which α and β are constants and f(t) and z(t) express the pulsating fractions in the blood flow F and the impedance Z, respectively. The correlation between the peak-to-peak values of f(t) and of adz(t)/dt+βz(t) was 0·96. The correlation between the mean flow fo and the peak-to-peak value of f(t) was 0·74. Furthermore, even when the mean flow was zero, adz(t) still existed. The theoretical model was tested against volume flow measurements made using an electromagnetic flowmeter and was found to correlate well. Theoretical estimates of vessel calibre also accord with measured values.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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