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  • 1
    Electronic Resource
    Electronic Resource
    Ceruletide therapy in action tremor following thalamic hemorrhage (1993)
    Springer
    Journal of neurology 240 (1993), S. 144-148 
    Details
    ISSN: 1432-1459
    Keywords: Ceruletide ; Cholecystokinin ; Thalamic tremor ; Action tremor ; Posteroventral lateral nucleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two men, aged 63 and 71 years, developed a gross action tremor and dysesthesias several months after an intracerebral hemorrhage. CT and MRI showed a small hemorrhage in the posterior region of the lateral nucleus of the thalamus in each patient. The tremor occurred on movement, had frequencies of 2.5-4.5 Hz and the amplitude varied depending on the joint position of the limb. Ceruletide (a cholecystokinin analog) 0.8 μg/kg i.m. produced a marked reduction in the action tremor and improved motor function. This effect appeared 10 15 min after the injection, and lasted for up to 4 weeks. It is suggested that ceruletide may be of value in the treatment of action tremors following a thalamic lesion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00857518
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Sweat function in Parkinson's disease (1994)
    Springer
    Journal of neurology 241 (1994), S. 573-576 
    Details
    ISSN: 1432-1459
    Keywords: Axon reflex ; Ceruletide ; Parkinson's disease ; Sweat function ; Sympathetic skin response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sweat function was studied in patients with Parkinson's disease and in normal adults by sympathetic skin response, the bromphenol blue printing method and the silicone mould method. In patients with Parkinson's disease, dysfunction of sweating was classified into two types: one type involved the postganglionic fibres and the other involved the preganglionic fibres or the central nervous system. The latter was observed in patients with milder disease and the former was observed in patients with severe disease. The progressive involvement of sweat function in Parkinson's disease may reflect spread from the central nervous system or preganglionic fibres to postganglionic fibres. In a few patients the results of sweat tests were normal. Ceruletide increased sweating in Parkinson's disease patients, and decreased the prolonged latency of the sympathetic skin response. It is hypothesized that ceruletide facilitates the preserved somatosympathetic reflex of sweating.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00920619
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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