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  • Abnormal tau  (2)
  • Chaos  (2)
  • Glutamate receptor  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Cloning, expression and modulation of a mouse NMDA receptor subunit
    Amsterdam : Elsevier
    FEBS Letters 300 (1992), S. 39-45 
    Details
    ISSN: 0014-5793
    Keywords: 12-O-Tetradecanoylphorbol 13-acetate ; Glutamate receptor ; Glycine ; Mg^2^+ block ; N-methyl-d-aspartate receptor channel
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)80160-I
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cloning and expression of the 4 subunit of the NMDA receptor channel
    Amsterdam : Elsevier
    FEBS Letters 313 (1992), S. 34-38 
    Details
    ISSN: 0014-5793
    Keywords: 4 subunit ; Functional expressions ; Glutamate receptor ; Molecular diversity ; N-Methyl-d-aspartate ; NMDA receptor channel ; Pharmacological diversity
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)81178-O
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Analytic study of chaos of the tent map: Band structures, power spectra, and critical behaviors (1983)
    Springer
    Journal of statistical physics 31 (1983), S. 279-308 
    Details
    ISSN: 1572-9613
    Keywords: Chaos ; mapping ; invariant measure ; ergodicity ; band structure of chaos ; power spectrum of chaos ; critical behavior ; scaling law ; Frobenius-Perron operator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Chaotic behaviors of the tent map (a piecewise-linear, continuous map with a unique maximum) are studied analytically throughout its chaotic region in terms of the invariant density and the power spectrum. As the height of the maximum is lowered, successive band-splitting transitions occur in the chaotic region and accumulate to the transition point into the nonchaotic region. The timecorrelation function of nonperiodic orbits and their power spectrum are calculated exactly at the band-splitting points and in the vicinity of these points. The method of eigenvalue problems of the Frobenius-Perron operator is used. 2 m−1 critical modes, wherem = 1,2, 3, ..., are found which exhibit the critical slowing-down near the 2 m−1-band to 2 m -band transition point. After the transition these modes become periodic modes which represent the cycling of nonperiodic orbits among 2 m bands together with the periodic modes generated by the preceding band splittings. Scaling laws near the transition point into the nonchaotic region are investigated and a new scaling law is found for the total intensity of the periodic part of the spectrum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01011583
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Keywords: Corticobasal degeneration ; Progressive supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294503
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy (1994)
    Springer
    Acta neuropathologica 88 (1994), S. 113-121 
    Details
    ISSN: 1432-0533
    Keywords: Key words: Corticobasal degeneration ; Progressive ; supranuclear palsy ; Neurofibrillary tangles ; Abnormal tau
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The neuropathological findings, including immunohistochemistry and electron microscopy, of two patients with clinical findings consistent with corticobasal degeneration (CBD) are reported. Both patients showed degeneration of the precentral cortex, the substantia nigra, the pallidum, and the thalamus. Many ballooned neurons were seen in the cerebral cortex, and argentophilic, skein-like inclusions suggesting neurofibrillary tangles (NFTs) were found in the brain stem and precentral cortex in patient 1. In contrast, patient 2 clearly showed NFTs in the brain stem and dentate nucleus which were indistinguishable from those seen in progressive supranuclear palsy (PSP), while only a few ballooned neurons were found in the cerebral cortex. Gallyas silver stain showed many argentophilic inclusions suggesting NFTs in the brain stem, subcortical nuclei, and cerebral cortex in both patients. Immunohistochemistry for tau showed tau-positive neurons in the cerebral cortex, brain stem, subcortical nuclei and spinal cord, and tau-positive glial cells were seen in the cerebral cortex, white matter and subcortical nuclei, and thread-like structures were seen in the cerebral cortex and white matter. Electron microscopy of the brain stem showed NFTs consisting of paired helical filaments in patient 1, and paired helical filaments and straight tubules in patient 2. Immunoelectron microscopy revealed parallel tau-positive filaments in the cerebral cortex in patent 1. From the two patients, the widespread appearance of abnormal tau and NFTs is one of the essential pathological features in CBD, and it also appears that CBD and PSP have some common underlying pathological processes. Patient 2 is closer to PSP than patient 1 and suggests CBD would link to PSP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294503
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Analytic study of power spectra of the tent maps near band-splitting transitions (1983)
    Springer
    Journal of statistical physics 30 (1983), S. 649-679 
    Details
    ISSN: 1572-9613
    Keywords: Chaos ; mapping ; ergodic ; mixing ; time-correlation function ; chaos-chaos transition ; Frobenius-Perron operator
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Successive band-splitting transitions occur in the one-dimensional map xi+1=g(xi),i=0, 1, 2,... withg(x)=αx, (0 ⩽x ⩽ 1/2) −αx +α, (1/2 〈x ⩽ 1) as the parameterα is changed from 2 to 1. The transition point fromN (=2n) bands to 2Nbands is given byα=(√2)1/N (n=0, 1,2,...). The time-correlation functionξ i=〈δxiδx0〉/〈(δx0)2,δxi≡ xi−〈xi〉 is studied in terms of the eigenvalues and eigenfunctions of the Frobenius-Perron operator of the map. It is shown that, near the transition pointα=√2,ξ i−[(10−4√2)/17] δi,0-[(10√2-8)/51]δi,1 + [(7 + 4√2)/17](−1)ie−yi, whereγ≡√2(α−√2) is the damping constant and vanishes atα=√2, representing the critical slowing-down. This critical phenomenon is in strong contrast to the topologically invariant quantities, such as the Lyapunov exponent, which do not exhibit any anomaly atα=√2. The asymptotic expression forξ i has been obtained by deriving an analytic form ofξ i for a sequence ofα which accumulates to √2 from the above. Near the transition pointα=(√2)1/N, the damping constant ofξ i fori ⩾N is given byγ N=√2(αN-√2)/N. Numerical calculation is also carried out for arbitrary a and is shown to be consistent with the analytic results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01009682
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    Paper (German National Licenses)
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