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  • Artikel: DFG Deutsche Nationallizenzen  (38)
  • Chemistry  (35)
  • Bacteriuria  (3)
  • 1
    Digitale Medien
    Digitale Medien
    The use of acridine orange staining and image analysis to detect bacteriuria (1985)
    Springer
    Urological research 13 (1985), S. 141-142 
    Details
    ISSN: 1434-0879
    Schlagwort(e): Bacteriuria ; Rapid detection ; Acridine Orange ; Fluorescence ; Image analysis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Fifty urine samples from a variety of urological patients were analysed using the fluorochrome acridine orange in an automated system. The results were compared with standard colony counts. The method has a potential value in the detection of significant infection particularly in population studies.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00256076
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  • 2
    Digitale Medien
    Digitale Medien
    The screening of more than 2,000 schoolgirls for bacteriuria using an automated fluorescence microscopy system (1985)
    Springer
    Urological research 13 (1985), S. 143-148 
    Details
    ISSN: 1434-0879
    Schlagwort(e): Bacteriuria ; Rapid detection ; Acridine Orange ; Fluorescence ; Bactoscan
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary After initial evaluation of a manual fluorescence microscopy system on a variety of urines the method was automated and subsequently tested in a population survey of urinary tract infection in schoolgirls. This automated Bactoscan system allowed a rapid analysis of urine samples and with the introduction of modifications to the staining protocol it correctly eliminated 91% of samples as being not significantly infected.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00256077
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  • 3
    Digitale Medien
    Digitale Medien
    A survey of bacteriuria in 2,234 schoolgirls in a Scottish new town (1985)
    Springer
    Urological research 13 (1985), S. 149-153 
    Details
    ISSN: 1434-0879
    Schlagwort(e): Bacteriuria ; Social habits ; Incontinence ; Schoolgirls
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The prevalence of urinary tract infection in a modern Scottish town has been ascertained in female school children aged 5–12. In 2,234 girls the initial prevalence of urinary tract infection is 3.3%. In addition to the information on urinary tract infection the social and personal history was available including data on incontinence, enuresis and current antibiotic therapy. The necessity to have a system available which allows a cheap and rapid assessment of population surveys is made.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00256078
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  • 4
    Digitale Medien
    Digitale Medien
    Experimental and theoretical studies of the three-dimensional structure of human interleukin-4 (1991)
    New York, NY : Wiley-Blackwell
    Proteins: Structure, Function, and Genetics 11 (1991), S. 111-119 
    Details
    ISSN: 0887-3585
    Schlagwort(e): interleukin-4 ; circular dichroism spectroscopy ; site-directed mutagenesis ; protein structure modeling ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin
    Notizen: The structure of human interleukin 4 (IL-4) was predicted utilizing a series of experimental and theoretical techniques. Circular Dichroism (CD) spectroscopy indicated that IL-4 belonged to the all α-helix class of protein structures. Secondary structure prediction, site-directed mutagenesis, and CD spectroscopy suggested a predominantly α-helical structure, consistent with a four-helix bundle structural motif. A human/mouse IL-4 chimera was constructed to qualitatively evaluate alternative secondary structure predictions. The four predicted helices were assembled into tertiary structures using established algorithms. The mapping of three disulfide bridges in IL-4 provided additional constraints on possible tertiary structures. Using accessible surface contact area as a criterion, the most suitable structures were right handed all antiparallel four-helix bundles with two overhand loop connections. Successful loop closure and incorporation of the three disulfide constraints were possible while maintaining the expected shape, solvent accessibility, and steric interactions between loops and helices. Lastly, energy minimization was used to regularize the chain.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prot.340110204
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  • 5
    Digitale Medien
    Digitale Medien
    Fast liquid chromatography for the resolution of chiral compounds (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 3 (1991), S. 188-195 
    Details
    ISSN: 0899-0042
    Schlagwort(e): fast analysis times ; enantiomers ; chiral stationary phase ; Pirkle-concept ; achiral derivatization ; rapid screening ; Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: A Pirkle-concept chiral stationary phase (CSP) derived from N-(1-naphthyl)leucine was evaluated for developing methods to reduce analysis times and investigating techniques in the rapid screening of a variety of chiral compounds over a given chiral selector. The effects of reduced column lengths and elevated temperatures were studied to shorten analysis times.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/chir.530030309
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  • 6
    Digitale Medien
    Digitale Medien
    Assignment of absolute configuration to an improved enantioselective naproxen selector (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Chirality 6 (1994), S. 615-622 
    Details
    ISSN: 0899-0042
    Schlagwort(e): absolute configuration ; chiral stationary phase ; enantiomer ; chiral recognition ; NSAID ; HPLC ; NMR ; CD ; X-ray ; Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Assignment of absolute configuration to a recently developed chiral selector useful in the separation of the underivatized enantiomers of naproxen and other nonsteroidal anti-inflammatory drugs (NSAIDs) is described. Circular dichroism, 1H NMR, and X-ray diffraction have been used to confirm the original assignment which was based solely upon elution orders from HPLC chiral stationary phases. All of these techniques agree in the assignment of the (S,S) absolute configuration to the enantiomer of the chiral selector which associates preferentially with (S)-naproxen. © 1994 Wiley-Liss, Inc.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/chir.530060803
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  • 7
    Digitale Medien
    Digitale Medien
    Optimization of capillary parameters for gas chromatography (1984)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 7 (1984), S. 382-388 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Gas chromatography ; Capillary columns ; HETP equation ; Optimum column parameters ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: An HETP equation for the capillary column is developed that takes into account the dependence of gaseous diffusion on pressure, the compressibility of the mobile phase, together with the unique relationship between mobile phase velocity, and the resistance to mass transfer in the stationary phase. The equation is used to develop a procedure for column optimization and expressions are derived that allow the optimum column radius and optimum column length to be calculated for a given fixed inlet pressure. It is shown that fast, simple separations are optimally achieved using relatively short small diameter columns. Conversely, optimum performance for the separation of complex mixtures requiring higher efficiencies requires the use of long columns with relatively large diameters.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240070708
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  • 8
    Digitale Medien
    Digitale Medien
    Retention tuning in the enantioseparation of naproxen esters and free acid (1997)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 20 (1997), S. 179-180 
    Details
    ISSN: 0935-6304
    Schlagwort(e): Enantiomers ; Chiral stationary phase ; Whelk-O ; Coelution ; Peak overlap ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Zusätzliches Material: 2 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/jhrc.1240200311
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  • 9
    Digitale Medien
    Digitale Medien
    Impact and compression response of composite materials containing fortifiers (1991)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 31 (1991), S. 1310-1315 
    Details
    ISSN: 0032-3888
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: The effect of adding fortifiers to an epoxy matrix on the response to impact and compression-after-impact properties of carbon fabric/epoxy laminates was investigated. The experimental work included determining laminate compression strength, absorbed energy from impact, damage area and compression-after-impact strength for an impact energy level of 21 joules per centimeter of thickness. This paper presents the results from this investigation and discusses the relationship between neat resin properties (with and without fortifiers) and the laminate properties.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pen.760311805
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  • 10
    Digitale Medien
    Digitale Medien
    Single photon counting imagery (1989)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 4 (1989), S. 507-511 
    Details
    ISSN: 0884-3996
    Schlagwort(e): Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Chemie und Pharmazie
    Notizen: Advent of the multichannel plate and position sensitive detector has made possible true single photon counting imaging tubes. We have investigated the application of these detectors in studies of the ultraweak light emission of biological materials. Initially, we focussed our efforts on two objectives: (1) obtaining single photon counting images of living tissues using only the light (chemiluminescence) emitted by the specimen and (2) developing means of obtaining well-resolved spectra of weakly emitting sources. We have obtained a variety of images. One striking result of this work is the first observation of tissue specific localization of photon emission in situ. Using this detector we have also obtained the first well-resolved spectra of some important ultraweak emission processes. These results illustrate the potential use of single photon imaging in bioluminescence and chemiluminescence research.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bio.1170040166
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