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  • 1
    Electronic Resource
    Electronic Resource
    Dose-related effects of selective 5-HT2 receptor antagonists on slow wave sleep in humans (1990)
    Springer
    Psychopharmacology 101 (1990), S. 568-569 
    Details
    ISSN: 1432-2072
    Keywords: Slow wave sleep ; 5-HT2/1c receptor ; Ritanserin ; ICI 169,369 ; Home sleep recordings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of the selective 5-HT2 receptor antagonists, ritanserin (1, 5 and 10 mg) and ICI 169,369 (50 and 100 mg), were studied on the sleep EEG of healthy volunteers using home-based Medilog 9000 cassette monitoring. Ritanserin (5 and 10 mg) produced a significant increase in slow wave sleep (SWS) while ICI 169,369 also increased SWS but only at a dose of 100 mg. These findings are consistent with the proposal that selective 5-HT2 receptor blockade increases SWS in humans; however, the data cannot exclude involvement of the closely related 5-HT1c receptor in this effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02244239
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  • 2
    Electronic Resource
    Electronic Resource
    Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin (1992)
    Springer
    Psychopharmacology 108 (1992), S. 387-389 
    Details
    ISSN: 1432-2072
    Keywords: Anxiety ; Slow wave sleep ; Ritanserin ; 5-HT2 receptor
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight patients with generalised anxiety disorder (GAD) and eight matched healthy controls had their polysomnogram measured on two occasions separated by 1 week. On one occasion they received the 5-HT2 receptor antagonist, ritanserin (5 mg orally) and on the other matching placebo. The increase in slow wave sleep produced by ritanserin was the same in GAD patients as in healthy controls. These findings do not support the hypothesis that GAD is associated with a generalised hypersensitivity of brain 5-HT2 receptors; however, the present data cannot exclude the presence of a regionally specific change in this receptor subtype in anxiety disorders.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02245128
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Solid-liquid-vapor phase behavior of the methane-carbon dioxide system (1962)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 8 (1962), S. 537-539 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The phase behavior of the methane-carbon dioxide system has been determined experimentally along the solid-liquid-vapor locus. Pressure-temperature measurements were made along this locus from the triple point of carbon dioxide to -284°F. Compositions of the vapor phase along the solid-liquid-vapor locus were determined with sampling techniques over a composition range of 0.1 to 12% carbon dioxide. Liquid-phase compositions were obtained from crystal-point determinations on eleven methane-carbon dioxide mixtures ranging from 0.16 to 20% carbon dioxide.With the pressure-temperature for the solid-liquid-vapor locus as the termination locus of the dew and bubble data of Donnelly and Katz (2), consistent liquid- and vapor-phase compositions were obtained over the remaining concentration range.Changes in the pressure-temperature relationship of the solid-liquid-vapor locus caused by using a methane stock containing 0.56 mole % nitrogen are also reported.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690080423
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  • 4
    Electronic Resource
    Electronic Resource
    Unbiased estimation of gross errors in process measurements (1992)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 38 (1992), S. 563-572 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A new approach to gross error detection provides unbiased estimates and 100(1-α)% simultaneous confidence intervals of process variables when biased process measurements and process leaks exist. Presented in this article are estimation equations for process variables, as well as equations that help identify biased measurements and process leaks. These equations include the power function for a global test, and two types of α-level component tests and their power functions. Important strengths and weaknesses of this approach are compared to those of the serial compensation strategy, in particular, by varying the significance level (α), the variance-covariance matrix (Σ), the size of measurement bias (δ), the number of biased variables, and the sample size (N). Accuracy of δ estimation and performance in detecting the presence of process leaks (γ) are also evaluated and compared. The proposed approach has unique features that can provide a basis for improving the reconciliation of variables in process operations.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690380410
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  • 5
    Electronic Resource
    Electronic Resource
    Fractionation with condensation and evaporation in wetted-wall columnsThis paper is not to be reproduced or published in any form without the written permission of the authors. J. F. Davis is now with the Department of Chemical Engineering, The Ohio State University. (1984)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 30 (1984), S. 328-338 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A model is presented to describe the behavior of falling film fractionators with evaporation or condensation. Experimental measurements of vapor composition, vapor temperature and wall temperature profiles were made. Close agreement suggests that the model is applicable to both adiabatic and nonadiabatic conditions.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690300223
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  • 6
    Electronic Resource
    Electronic Resource
    The heterogeneous phase behavior of the helium-nitrogen system (1964)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 10 (1964), S. 937-943 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690100631
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  • 7
    Electronic Resource
    Electronic Resource
    Fractionating condensation and evaporation in plate-fin devices (1986)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 32 (1986), S. 1116-1124 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A model that describes fractionation with condensation and evaporation in a plate-fin device has been formulated. It is capable of evaluating profiles of composition, temperature, and flow rate for both liquid and vapor streams in an extended surface device. The device may be adiabatic or nonadiabatic and the surface may be incompletely wetted. Compared to experimental measurements, the model predictions showed ± 1 number of transfer unit deviation along the length of the device. The predictions of the top and bottom flow rate ratio showed a 5-10% deviation for adiabatic and condensation runs and a 25% deviation for evaporation runs.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690320708
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  • 8
    Electronic Resource
    Electronic Resource
    Gross error detection when variance-covariance matrices are unknown (1993)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 39 (1993), S. 1335-1341 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Equations introduced here identify measurement biases and process leaks, when gross errors exist in measured process variables and the variance-covariance matrix of the measurements, Σ, is unknown. Σ is estimated by the sample variance, S, using process data.For an unknown Σ, the global test statistic is the well-known Hotelling T2 statistic. Its power function has a noncentral F-distribution. For component tests used for specific identification of measurement biases and nodal leaks, two tests are presented with Σ unknown. The first test is independent of the number of component tests, k, and is given by a statistic with an F-distribution. The second test depends on k and has a student t-distribution. The power functions for both component tests are provided. Process examples and a Monte Carlo simulation study presented demonstrate the use and performance of these statistical equations in identifying biases and process leaks.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690390810
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  • 9
    Electronic Resource
    Electronic Resource
    The search for correlation between electrokinetic phenomena and blood thrombus formation on implant materials (1968)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 2 (1968), S. 51-79 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Bioelectric charge transfer at the blood-wall interface may be a crucial factor affecting thrombosis on implant materials. A program of studies was conducted to determine the electrokinetic and other physical properties of a wide spectrum of materials including organic polymers, metals, inorganics, heterogeneous compounds, and animal tissue. From these tests, materials were selected for in-vivo cannulation experiments. In this manner, a search was made to find a correlation between surface charge characteristics and thrombosis on cardiovascular implant materials. It was found that materials exhibiting a substantial positive charge were prone to rapid thrombosis. No clear correlation can be stated, as yet, regarding the thrombogenecity of highly charged negative surfaces or slightly charged surfaces. However, many heterogeneous materials have exhibited prolonged in-vivo patency. It appears necessary to isolate surface effects from volumetric effects to seek the role of bioelectric charge transfer in blood thrombus formation.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820020105
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    On wave propagation in viscoelastic media (1961)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Polymer Science 50 (1961), S. 475-488 
    Details
    ISSN: 0022-3832
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: A mathematical analysis is made of the problem of wave propagation in a one-dimensional bounded viscoelastic medium under prescribed boundary conditions. Closed form expressions are obtained for viscoelastic waves for the case of a relaxation function involving a single relaxation time. An expression for the phase velocity as a function of ratio of relaxation frequency to frequency of applied periodic displacement is obtained for the steady state part of the solution. The generalization to a relaxation function involving a finite number of relaxation times is discussed, and a method is sketched out for solving the more general integropartial differential equation of motion. Comments are made on the molecular interpretation of viscoelastic models.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pol.1961.1205015416
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