ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The preparation of the optically pure tritertiary phosphine (RRR)-MeSi(CH2P(t-Bu)Ph)3 (2) is reported. The route followed involves deprotonation of optically pure (R)-P(BH3)Me(t-Bu)PH (2) the reaction of the resulting carbanion with MeSiCl3, followed by removal with morpholine of the BH3-protecting groups from the triertiary phosphine-borane 3. The latter's X-ray crystal structure and that of [Rh(NBD)((RRR)-1]TOf)(4), are also rported. Furthermore, it is shown that the separation of the racemic phosphine-borane 2 can be conveniently carried out using medium-pressure liquid chromatgrapy with cellulose-riacetate as a chiral stationary phase.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19910740508
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