ISSN:
1612-1112
Keywords:
Ligand exchange chromatography
;
Chiral mobile phase
;
Enantiomer separation
;
Natural pterins
;
Colpidium campylum
;
Astasia longa
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The separation of the D and L enantiomers of biopterin and neopterin has been achieved by ligand exchange chromatography using a reversed phase column with a mobile phase containing D-phenylalanine as chiral modifier and Cu(II) as the metal ion. This successful separation has enabled the identification of natural pterins present in various protozoans by comparison with authentic, optically pure compounds. D-monapterin and D-neopterin were identified in the ciliate protozoanColpidium campylum. L-biopterin has been found, for the firs time, in a flagellate protozoan,Astasia longa.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02263840
Permalink
