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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 38 (1995), S. 509-513 
    ISSN: 1530-0358
    Keywords: Colon ; Innervation ; Nerves ; Muscle ; Immunohistochemistry ; Constipation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: This study was designed to investigate neural and muscular features of the colonic wall in patients with severe idiopathic constipation. METHODS: By using quantitative immunohistochemistry, resected specimens from 14 patients with idiopathic chronic constipation and 17 nonobstructed cancer controls were studied. RESULTS: Routine histology revealed no significant histologic abnormality throughout the colon apart from four cases of melanosis coli. Ratio of the thickness of circular to longitudinal muscle was significantly lower in the left colon in constipated subjects. The myenteric plexus appeared morphologically normal in all subjects. S-100 protein, which stains neuronal supporting tissues, demonstrated an increase in the proportion of neural tissue in the myenteric plexus. There was an increased number of PGP-9.5 immunoreactive nerve fibers in the muscularis propria in constipated patients, and this was significantly higher in the ascending and descending colon. CONCLUSION: Intractably constipated patients have alterations in the neural composition of the colonic myenteric plexus and innervation of the circular muscle.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    BIT 36 (1996), S. 247-263 
    ISSN: 1572-9125
    Keywords: Block downdating ; Cholesky decomposition ; condition number ; error analysis ; perturbation theory ; seminormal equations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract A new perturbation result is presented for the problem of block downdating a Cholesky decompositionX T X = R T R. Then, a condition number for block downdating is proposed and compared to other downdating condition numbers presented in literature recently. This new condition number is shown to give a tighter bound in many cases. Using the perturbation theory, an error analysis is presented for the block downdating algorithms based on the LINPACK downdating algorithm and stabilized hyperbolic transformations. An error analysis is also given for block downdating using Corrected Seminormal Equations (CSNE), and it is shown that for ill-conditioned downdates this method gives more accurate results than the algorithms based on the LINPACK downdating algorithm or hyperbolic transformations. We classify the problems for which the CSNE downdating method produces a downdated upper triangular matrix which is comparable in accuracy to the upper triangular factor obtained from the QR decomposition by Householder transformations on the data matrix with the row block deleted.
    Type of Medium: Electronic Resource
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