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  • 1
    Electronic Resource
    Electronic Resource
    Serum elastase 1 in chronic pancreatic disease (1985)
    Springer
    Journal of molecular medicine 63 (1985), S. 603-606 
    Details
    ISSN: 1432-1440
    Keywords: Elastase 1 ; Trypsin ; Radioimmunoassay ; Chronic pancreatitis ; Pancreatic cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Elastase 1 and immunoreactive trypsin were assessed by a RIA technique in the sera of 29 control subjects, 24 pancreatic cancer patients, 22 patients with chronic pancreatitis and 31 with extra-pancreatic diseases to ascertain and compare their usefulness in chronic pancreatic disease diagnosis. Increased levels of elastase 1 were detected in 60.9% of pancreatic cancer and in 61.1% of chronic pancreatitis patients; low values were found in only two subjects with pancreatic disease. A close correlation between the two enzymes was found in patients suffering from pancreatic cancer and chronic pancreatitis. These data suggest that serum elastase 1, as well as immunoreactive trypsin, is of limited value in chronic pancreatic disease diagnosis; increased levels of the two enzymes always occur simultaneously; low immunoreactive trypsin values together with normal elastase 1 serum levels are detectable in a number of patients with chronic pancreatitis and severe exocrine insufficiency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01733013
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Pancreolauryl test in chronic pancreatitis (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 1222-1223 
    Details
    ISSN: 1432-1440
    Keywords: Pancreatic function test ; Pancreolauryl test ; Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pancreolauryl test was performed in 30 subjects with chronic pancreatitis, in order to evaluate its behavior in relation to the duration of the clinical history and the presence of pancreatic calcifications, diabetes mellitus, jaundice, and pancreatic pseudocysts. A significant inverse linear correlation was found between the onset of symptoms and FDL test values. While calcifications and diabetes were present in patients with both normal and abnormal test results, those with pseudocysts or jaundice always had pathological results.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01734461
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Study of retinol-binding protein in pancreatic cancer (1984)
    Springer
    Journal of cancer research and clinical oncology 108 (1984), S. 227-229 
    Details
    ISSN: 1432-1335
    Keywords: Retinol-binding protein ; Prealbumin ; Zinc ; Pancreatic cancer ; Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Serum RBP, prealbumin, and zinc were evaluated in normal subjects and patients with pancreatic cancer and chronic pancreatitis. A significant decrease of RPB was found in pancreatic cancer patients compared with controls. A concomitant reduction of prealbumin and zinc was also observed. Multiple regression analysis suggested that the modification of RBP serum levels might be accounted for mainly by diminished prealbumin levels, while the direct role of zinc is negligible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00402471
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Tumor-associated trypsin inhibitor in patients with chronic pancreatic diseases (1989)
    Springer
    Journal of molecular medicine 67 (1989), S. 1029-1032 
    Details
    ISSN: 1432-1440
    Keywords: Trypsin inhibitors ; Tumor markers ; Pancreatic enzymes ; Pancreatic cancer ; Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Serum TATI (tumor-associated trypsin inhibitor) was measured in 41 control subjects, 30 patients with pancreatic cancer, 53 with chronic pancreatitis, and 47 with extrapancreatic diseases, mainly of gastrointestinal origin. TATI was found to be elevated in some subjects in all groups of patients; patients with chronic pancreatitis studied during an acute exacerbation of the disease had the highest percentage (68%) of pathological values. TATI was found to be correlated with elastase 1, tissue polypeptide antigen, and total and pancreatic isoamylase. A significant relationship was also found between TATI and serum creatinine levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01727004
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    Paper (German National Licenses)
    Fulltext
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