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  • 1
    Electronic Resource
    Electronic Resource
    Numerical simulation of sea water intrusion near Beihai, China (2000)
    Springer
    Environmental geology 40 (2000), S. 223-233 
    Details
    ISSN: 1432-0495
    Keywords: Keywords Coastal aquifers ; Seawater intrusion ; Leaky aquifer system ; Numerical modeling ; Numerical simulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  A leaky aquifer system occurs in the coastal plain near Beihai, China. Seawater intrusion into the confined aquifer took place along the northern coast. Chloride concentrations at some observation wells increased steadily from 1988 and were at their peak in 1993. A quasi-three-dimensional element model has been developed to simulate the spatial and temporal evolution of hydraulic heads and chloride concentrations of the groundwater near the northern coast. The simulation model was based on the transition zone approach, which requires simultaneous solution of the governing water flow and solute transport equations. An irregular grid of a quadrangle was used to discretize the flow domain. Various aquifer parameters were verified with the numerical model in order to obtain satisfactory matches between computed values and observed data from an investigation. Three pumpage schemes were designed to use the calibrated model for prediction of future changes in water levels and chloride concentrations in groundwater in the study area. Results show that seawater intrusion would worsen in the confined aquifer if the current rates of groundwater pumpage continue. The alternative, to eliminate pumpage in the intruded area and to moderate pumpage rates from water supply wells far from the seashore, may limit seawater intrusion significantly and is considered attractive in the area.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540000113
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    In vitro activity of meropenem and four other antibiotics against 554 clinical strains obtained from Beijing in 1999 (2000)
    Springer
    Journal of infection and chemotherapy 6 (2000), S. 178-183 
    Details
    ISSN: 1437-7780
    Keywords: Key words Meropenem ; β-Lactams ; Clinical isolated strains ; MIC (E-test)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 1999, a surveillance study was initiated in a hospital in Beijing to monitor the potency and spectrum of five extended-spectrum β-lactam antimicrobial agents (meropenem, imipenem, cefepime, ceftazidime, and cefoperazone/sulbactam) tested against 554 strains of bacteria. Five groups of organisms were tested by the E-test method, with results validated by concurrent quality control strain analysis. Results were tabulated, and 100% of quality assurance tests (16/16 tests) were within ranges recommended by the National Committee for Clinical Laboratory Standards. Of the five β-lactam drugs tested, meropenem and imipenem were the most active against all isolates tested. Overall, the rank order of activity of the five agents was: meropenem (94.6% susceptible) 〉 imipenem (90.1%) 〉 cefepime (77.6%), cefoperazone/sulbactam (77.5%), ceftazidime (76.6%). Ninety-five percent of Enterobacter were to meropenem, while 82% were susceptible to imipenem. Meropenem was more active than imipenem against Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) of meropenem was eightfold lower than that of imipenem. Meropenem had excellent activity against Haemophilus influenzae, Streptococcus pneumoniae, and oxacillin-susceptible staphylococci.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101560070019
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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