ISSN:
1434-4726
Keywords:
Hearing development
;
Cochlear synaptogenesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Maturation of hamster cochlea was studied using light and electron microscopy. Critical stages of receptor and neural structure development have been determined. At birth the hamster cochlea shows a pronounced immaturity, but innervation can already be found. 2 or 3 days later, characteristic afferent synapses can be recognized beginning at the inner hair cell level. Similarly, efferent endings first appear on the inner side at the end of the first week. The onset of auditory function must be related to structures depicted at around 10 days, and cochlear maturation is achieved at about 25 days. The sequence of synaptic development in the cochlea is discussed regarding the general morphogenesis of synapses within the nervous system. Some determinations of the timing of peripheral myelination are given. This process begins almost a week before the presumable date of the onset of function.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00453886
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