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  • 1
    Electronic Resource
    Electronic Resource
    Zum enzymatisch-immunochemischen Nachweis des Haschischkonsums und seiner dünnschichtchromatographischen Absicherung (1985)
    Springer
    International journal of legal medicine 94 (1985), S. 219-225 
    Details
    ISSN: 1437-1596
    Keywords: Cannabinoids, enzyme immunoassay ; THC-metabolite, detection in urine and blood ; Cannabinoide, Enzymimmunoassay ; THC-Metabolit, Nachweis in Urin und Blut
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Mit Hilfe des Enzymimmunoassay (EMIT-dau-Syva) lassen sich Cannabinoide in Blut und Urin nach inhalativer (10 mg THC) oder oraler (30 mg THC) Aufnahme nachweisen. Die Kurvenverläufe werden mitgeteilt. Im Urin waren erhöhte Spiegel bis zu einer Woche nachweisbar. Eine Absicherung der EMIT-Befunde ist mittels Dünnschichtchromatographie nach absorptiver Anreicherung an einer C18-Extraktionssäule möglich. Nachweisgrenze ist 10 ng THC-Carbonsäure/ml bei Einsatz von 10 ml Urin.
    Notes: Summary The EMIT cannabinoid assay was used for screening blood and urine after smoking tetrahydrocannabinol (THC; 10 mg) or ingestion of THC (30 mg). Cannabinoid levels in urine remain detectable up to 1 week. Confirmation was done by adsorption of the THC carboxylic acid onto a C18 extraction column and elution with acetone and TLC. The method is simple and sensitive and is applicable with common laboratory equipment. The detection limit is 10 ng/ml, using 10 ml urine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204086
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  • 2
    Electronic Resource
    Electronic Resource
    HEMOCO: a French prospective study of hemophiliacs infected by human immunodeficiency virus type 1 (HIV-1) (1997)
    Springer
    Hematology and cell therapy 38 (1997), S. 193-198 
    Details
    ISSN: 1279-8509
    Keywords: Hemophilia ; Human immunodeficiency virus (HIV) ; Cohort ; Age ; AIDS ; Death
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract HEMOCO is a multicenter prospective cohort set up in 1989 to monitor 407 French hemophiliacs infected by HIV-1 and recruited in 4 hemophilia treatment centers in the Paris region. As of 15 July 1995, 42% of the patients in the cohort had developed stage B HIV disease and 29% stage C disease (AIDS); 23.1% of the patients had died. The cumulative proportion of patients with AIDS was 4.5% at 5 years and 27.4% at 10 years, while the respective mortality rates were 3.8% and 19.5%. In our study, only age was predictive of AIDS, with an estimated relative risk of 1.2 per 10-year age increment; this factor was also predictive of death. After 10 years of follow-up, 6.1% of the study population had no clinical or laboratory signs of immunodepression. The follow-up protocol in the HEMOCO protocol is the same as that in the French SEROCO study, which includes men infected by HIV-1 through sexual contact. This will allow us to compare the progression of HIV infection between these two exposure groups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00282-996-0193-7
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    Paper (German National Licenses)
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