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  • Colectomy  (1)
  • Keywords: Sphingomonas; macromolecule transport; pit; polysaccharide lyase; ABC transporter  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 372 (1987), S. 399-399 
    ISSN: 1435-2451
    Keywords: Colectomy ; Proctomucosectomy with ileo-anal anastomosis ; Maximal anal canal pressure at rest ; Colektomie ; Proktomucosektomie mit ileo-analer Anastomose ; Maximaler Analkanaldruck in der Ruhephase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1978 wurden 54 Patienten (37 Adenomatosis coli und 17 Colitis ulcerosa) durch Colektomie, Proktomucosektomie mit ileo-analer Anastomose operiert. Dabei wurde die rectale Mucosa ausgehend von einem Punkt oberhalb des peritonealen Bodens, und hinab bis zur Linea dentata abgeschält. Die Patienten, bei denen der maximale Analkanaldruck in der Ruhephase nach der Operation grössber als 60 cm Wassersäule war, zeigten alle ausgezeichnete bis gute faecale Tätigkeit. Hinsichtlich des Taschentyps ist eine J-förmige Tasche in der rectalen Mucosastulpe vorzuziehen.
    Notes: Summary Since 1978, 54 patients (37 adenomatosis coli and 17 colitis ulcerosa) have undergone colectomy, proctomucosectomy with ileo-anal anastomosis. The rectal mucosa was stripped out beginning at the level above the peritoneal floor and down to just above the dentate line. All the patients, in which the maximal anal canal pressure at rest was more than 60 cm water column after the operation, showed excellent or good fecal function. As to the pouch type constructed, J-formed pouch is most favourable.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1476-5535
    Keywords: Keywords: Sphingomonas; macromolecule transport; pit; polysaccharide lyase; ABC transporter
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A bacterium isolated from soil as an alginate lyase producer shows characteristic morphological and taxonomical properties consistent with being classified in the genus Sphingomonas. The bacterium utilizes high molecular weight (HMW)-alginate for growth by depolymerization of the polymer with intracellular alginate lyases, which are generated from a common precursor protein through autoregulated post-translational modifications. Electron microscopic observations of the cell surface and of thin sections of cells grown on HMW-alginate revealed dynamic changes in both cell surface and membrane structures. The most remarkable change is recognized in the formation of mouth-like pits which open and close depending on the presence or absence of HMW-alginate. Enzymatic and genetic analyses of HMW-alginate incorporation processes confirmed the presence of a pit-dependent and macromolecule-specific ABC transporter system in cells of Sphingomonas species A1. This is the first description of a bacterium with a pit on the cell surface and a pit-dependent endocytosic uptake system for macromolecules.
    Type of Medium: Electronic Resource
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