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  • 1
    Electronic Resource
    Electronic Resource
    Long-term observation of the detrusor smooth muscle in rats (1990)
    Springer
    Urological research 18 (1990), S. 439-442 
    Details
    ISSN: 1434-0879
    Keywords: Detrusor smooth muscle ; Rats ; Estrogen ; Collagen concentration ; Bladder
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We studied the bladders of 24-month-old intact rats, rats that had been ovariectomized at the age of 6 months, and intact and ovariectomized rats treated by estrogen from the age of 16 months. The study thus comprized four groups: group I: bilaterally ovariectomized rats; group II: intact rats; group III: ovariectomized rats treated with estrogen; group IV: intact rats treated with estrogen. The weight and collagen concentration of the bladders were determined. The ovariectomized bladders weighed significantly less and had a higher collagen concentration than the intact bladders. Estrogen substitution for ovariectomized rats reversed these parameters. Detrusor strips were also used for organ bath studies. All bladders were similar in regard to the nervemediated frequency-response relationship. The atropine-resistant response was studied by adding scopolamine to the organ bath. Strips from ovariectomized rats had a significantly diminished atropine-resistant response, which was abolished by estrogen substitution. The present study suggests that micturition problems in menopause might have a structural as well as a pharmacological explanation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00297382
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    MRI of voluntary pelvic floor contractions in healthy female volunteers (1995)
    Springer
    International urogynecology journal 6 (1995), S. 138-152 
    Details
    ISSN: 1433-3023
    Keywords: Bladder ; Continence ; Levator ani ; Physiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The dynamic anatomical response of the normal pelvic floor to voluntary pelvic floor contractions was documented using magnetic resonance imaging. Sequences of coronal, sagittal and transverse images in the relaxed and the contracted state were obtained from 17 young, asymptomatic volunteers trained to perform pelvic floor exercises correctly. The images were processed digitally and computer colored to indicate dynamic changes produced as a result of contractions. Gross transverse sections through a human female cadaver were photographed and digitized to provide a reference of pelvic anatomy. A 3D rendition of the processed MR images was made to illustrate the extent of pelvic floor contraction. The results illustrate the changes produced by voluntary pelvic floor contractions in all planes scanned. Quantitative measurements of selective structures around the bladder were made to show the magnitude of pelvic floor displacement during contraction. The dynamic imaging illustrates the extent of changes in the normal pelvic floor that are produced by pelvic floor exercises and give a measure of the displacement of the bladder and the levator ani.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01900574
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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