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Digitale Medien

MRI assessment of cerebral blood volume in patients with brain infarcts (1998)

Wu, R. H. ; Bruening, R. ; Berchtenbreiter, C. ; [weitere]

Springer

Neuroradiology 40 (1998), S. 496-502

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ISSN: 1432-1920

Schlagwort(e): Key words Magnetic resonance imaging ; Perfusion studies ; Dynamic contrast-enhanced imaging ; Cerebral blood volume ; Brain infarcts

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract MRI perfusion studies have focussed mainly on acute ischaemia and characterisation in ischaemia. Our purpose was to analyse regional brain haemodynamic information in acute, subacute, and chronic ischaemia. We performed 16 examinations of 11 patients on a 1.5 T MR images. Conventional and dynamic contrast-enhanced imaging were employed in all examinations. For the dynamic susceptibility sequences, a bolus (0.2 mmol/kg) of gadopentetate dimeglumine was injected. Reconstructed regional relative cerebral blood volume (rCBV) maps, bolus maps, and conventional images were analysed by consensus reading. In all examinations decreases in rCBV were observed in the lesions. The distribution of regional rCBV in lesions was heterogeneous. The rCBV of the periphery of the lesions was higher than that at their center. There was a correlation between the time since onset and abnormalities on the rCBV map and T2-weighted images (T2WI). In the early stage of acute stroke, the abnormalities tended to be larger on the rCBV than on T2WI. Many patterns of bolus passage were observed in ischaemic regions. rCBV maps provide additional haemodynamic information in patients with brain infarcts.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s002340050632

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Digitale Medien

Comparison of the performance of various gradient-corrected exchange and correlation functionals in density functional theory: Case studies of CO and N2O molecules (1995)

Chermette, H. ; Lembarki, A. ; Gulbinat, P. ; [weitere]

New York, NY : Wiley-Blackwell

International Journal of Quantum Chemistry 56 (1995), S. 753-762

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ISSN: 0020-7608

Schlagwort(e): Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: An investigation of the influence of various gradient-corrected exchange and correlation functionals on the bond lengths and dipole moments of CO and N2O has been carried out using density functional theory. It is shown that whereas some functionals are found to be more sensitive to the basis set quality than are others, the more commonly used gradient-corrected functionals lead to properties in very good agreement with experiment provided that a sufficiently large basis set is employed. © 1995 John Wiley & Sons, Inc.

Zusätzliches Material: 5 Ill.