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MRI assessment of cerebral blood volume in patients with brain infarcts (1998)

Wu, R. H. ; Bruening, R. ; Berchtenbreiter, C. ; [et al.]

Springer

Neuroradiology 40 (1998), S. 496-502

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ISSN: 1432-1920

Keywords: Key words Magnetic resonance imaging ; Perfusion studies ; Dynamic contrast-enhanced imaging ; Cerebral blood volume ; Brain infarcts

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract MRI perfusion studies have focussed mainly on acute ischaemia and characterisation in ischaemia. Our purpose was to analyse regional brain haemodynamic information in acute, subacute, and chronic ischaemia. We performed 16 examinations of 11 patients on a 1.5 T MR images. Conventional and dynamic contrast-enhanced imaging were employed in all examinations. For the dynamic susceptibility sequences, a bolus (0.2 mmol/kg) of gadopentetate dimeglumine was injected. Reconstructed regional relative cerebral blood volume (rCBV) maps, bolus maps, and conventional images were analysed by consensus reading. In all examinations decreases in rCBV were observed in the lesions. The distribution of regional rCBV in lesions was heterogeneous. The rCBV of the periphery of the lesions was higher than that at their center. There was a correlation between the time since onset and abnormalities on the rCBV map and T2-weighted images (T2WI). In the early stage of acute stroke, the abnormalities tended to be larger on the rCBV than on T2WI. Many patterns of bolus passage were observed in ischaemic regions. rCBV maps provide additional haemodynamic information in patients with brain infarcts.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s002340050632

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Comparison of the performance of various gradient-corrected exchange and correlation functionals in density functional theory: Case studies of CO and N2O molecules (1995)

Chermette, H. ; Lembarki, A. ; Gulbinat, P. ; [et al.]

New York, NY : Wiley-Blackwell

International Journal of Quantum Chemistry 56 (1995), S. 753-762

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ISSN: 0020-7608

Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: An investigation of the influence of various gradient-corrected exchange and correlation functionals on the bond lengths and dipole moments of CO and N2O has been carried out using density functional theory. It is shown that whereas some functionals are found to be more sensitive to the basis set quality than are others, the more commonly used gradient-corrected functionals lead to properties in very good agreement with experiment provided that a sufficiently large basis set is employed. © 1995 John Wiley & Sons, Inc.

Additional Material: 5 Ill.